Controlling cell membrane potential with static nonuniform magnetic fields

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F23%3A00571969" target="_blank" >RIV/68378271:_____/23:00571969 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/chapter/10.1007/978-981-19-8869-1_5" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-19-8869-1_5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-19-8869-1_5" target="_blank" >10.1007/978-981-19-8869-1_5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Controlling cell membrane potential with static nonuniform magnetic fields

Popis výsledku v původním jazyce

The coordinated activity of a myriad of ion channels in a cell is a spectacular biological and physical phenomenon. Understanding mechanisms governing the ion channel gating and setting membrane potentials is key to developing targeted therapeutic strategies using non-contact magnetic stimulations. In this study, we demonstrate theoretically that ion channel activity can be controlled by a static gradient magnetic field. The analysis revealed that specific ion membrane channels can be turned off and on by remotely applying a high gradient magnetic field, thus modulating the cell membrane potentials. The suggested model and mechanisms provide a general framework for identifying possible hidden mechanisms of biomagnetic effects associated with modulation of ion channel activity by high gradient static magnetic fields.

Název v anglickém jazyce

Controlling cell membrane potential with static nonuniform magnetic fields

Popis výsledku anglicky

The coordinated activity of a myriad of ion channels in a cell is a spectacular biological and physical phenomenon. Understanding mechanisms governing the ion channel gating and setting membrane potentials is key to developing targeted therapeutic strategies using non-contact magnetic stimulations. In this study, we demonstrate theoretically that ion channel activity can be controlled by a static gradient magnetic field. The analysis revealed that specific ion membrane channels can be turned off and on by remotely applying a high gradient magnetic field, thus modulating the cell membrane potentials. The suggested model and mechanisms provide a general framework for identifying possible hidden mechanisms of biomagnetic effects associated with modulation of ion channel activity by high gradient static magnetic fields.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Biological effects of static magnetic fields

ISBN

978-981-19-8868-4

Počet stran výsledku

19

Strana od-do

113-131

Počet stran knihy

420

Název nakladatele

Springer Singapore

Místo vydání

Singapore

Kód UT WoS kapitoly

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