Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F13%3A00213707" target="_blank" >RIV/68407700:21220/13:00213707 - isvavai.cz</a>

Výsledek na webu

<a href="http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6707382&tag=1" target="_blank" >http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6707382&tag=1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/EHB.2013.6707382" target="_blank" >10.1109/EHB.2013.6707382</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering

Popis výsledku v původním jazyce

Biological prostheses of human heart valves are prepared from autologous heart valves and from xenogeneic heart valves or pericardium. Xenogenous and allogenous biological prostheses are associated with adverse immune reactions, thrombosis and degeneration, and thus they have a high rate of reoperation. An optimum autologous tissue for heart valve grafts therefore needs to be found. Human pericardium was assessed as a potential source, and was compared with native human heart valves and porcine and bovine pericardium and heart valves. The tissues were evaluated for their mechanical properties, their collagen content and structure, and their histological structure. We observed differences in mechanical properties, collagen fibre orientation, the shape of the collagen bundles, and the collagen content among the pericardium samples and heart valves of different origin.

Název v anglickém jazyce

Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering

Popis výsledku anglicky

Biological prostheses of human heart valves are prepared from autologous heart valves and from xenogeneic heart valves or pericardium. Xenogenous and allogenous biological prostheses are associated with adverse immune reactions, thrombosis and degeneration, and thus they have a high rate of reoperation. An optimum autologous tissue for heart valve grafts therefore needs to be found. Human pericardium was assessed as a potential source, and was compared with native human heart valves and porcine and bovine pericardium and heart valves. The tissues were evaluated for their mechanical properties, their collagen content and structure, and their histological structure. We observed differences in mechanical properties, collagen fibre orientation, the shape of the collagen bundles, and the collagen content among the pericardium samples and heart valves of different origin.

Druh

D - Stať ve sborníku

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

4th IEEE International Conference on e-Health and Bioengineering EHB 2013

ISBN

978-1-4799-2372-4

ISSN

—

e-ISSN

—

Počet stran výsledku

4

Strana od-do

1-4

Název nakladatele

Gr. T. Popa University of Medicine and Pharmacy

Místo vydání

Iasi

Místo konání akce

Iasi

Datum konání akce

21. 11. 2013

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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