Effect of axial prestretch and adipose tissue on the inflation-extension behavior of the human abdominal aorta

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F20%3A00338064" target="_blank" >RIV/68407700:21220/20:00338064 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1080/10255842.2019.1699544" target="_blank" >https://doi.org/10.1080/10255842.2019.1699544</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10255842.2019.1699544" target="_blank" >10.1080/10255842.2019.1699544</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of axial prestretch and adipose tissue on the inflation-extension behavior of the human abdominal aorta

Popis výsledku v původním jazyce

Our study aims to show that perivascular adipose tissue may significantly change the mechanical state of the abdominal aorta. To this end, uniaxial tensile tests with perivascular fat tissue were carried out. In the subsequent regression analysis, stress-strain data were fitted by the polynomial strain energy density. A constitutive model of adipose tissue was used in the analytical simulation of the inflation-extension behavior of the human abdominal aorta. The computational model was based on the theory of the bi-layered thick-walled tube. In addition to the effect of perivascular tissue, the effect of axial prestretch was also studied. It was found that the presence of perivascular tissue reduces the distensibility of the aorta. Axial prestretch applied to the aorta embedded in adipose tissue had an effect opposite to that of adipose tissue. Axially prestrained aorta exhibited higher distensiblity than non-prestrained aorta. It was also shown that the perivascular envelope bears some portion of the pressure loading and thus reduces the mechanical stresses inside the wall of aorta. A similar effect was found for axial prestretch.

Název v anglickém jazyce

Effect of axial prestretch and adipose tissue on the inflation-extension behavior of the human abdominal aorta

Popis výsledku anglicky

Our study aims to show that perivascular adipose tissue may significantly change the mechanical state of the abdominal aorta. To this end, uniaxial tensile tests with perivascular fat tissue were carried out. In the subsequent regression analysis, stress-strain data were fitted by the polynomial strain energy density. A constitutive model of adipose tissue was used in the analytical simulation of the inflation-extension behavior of the human abdominal aorta. The computational model was based on the theory of the bi-layered thick-walled tube. In addition to the effect of perivascular tissue, the effect of axial prestretch was also studied. It was found that the presence of perivascular tissue reduces the distensibility of the aorta. Axial prestretch applied to the aorta embedded in adipose tissue had an effect opposite to that of adipose tissue. Axially prestrained aorta exhibited higher distensiblity than non-prestrained aorta. It was also shown that the perivascular envelope bears some portion of the pressure loading and thus reduces the mechanical stresses inside the wall of aorta. A similar effect was found for axial prestretch.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20302 - Applied mechanics

Projekt

<a href="/cs/project/GA18-26041S" target="_blank" >GA18-26041S: Vliv podélného předepnutí na mechanickou odezvu nelineárních elastických a viskoelastických trubic</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Computer Methods in Biomechanics and Biomedical Engineering

ISSN

1025-5842

e-ISSN

1476-8259

Svazek periodika

23

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

81-91

Kód UT WoS článku

000501422300001

EID výsledku v databázi Scopus

2-s2.0-85076359192