NONLINEAR CELL DEFORMATION MODEL

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F23%3A00369524" target="_blank" >RIV/68407700:21220/23:00369524 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21460/23:00369524

Výsledek na webu

<a href="https://doi.org/10.2478/scjme-2023-0026" target="_blank" >https://doi.org/10.2478/scjme-2023-0026</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/scjme-2023-0026" target="_blank" >10.2478/scjme-2023-0026</a>

Jazyk výsledku

angličtina

Název v původním jazyce

NONLINEAR CELL DEFORMATION MODEL

Popis výsledku v původním jazyce

Cytoskeletal mechanics is a field that heavily relies on mathematical models to interpret experimental data related to forces and deformations. In this paper, we present a novel mathematical model designed specifically for analysing the mechanical properties of liposomes, which serve as model systems for studying biological membranes. Our model takes into account various factors such as stretching, bending, and contact adhesion during atomic force microscopy (AFM) indentation using a spherical tip. By applying our model to liposomes, we demonstrate that these structures exhibit nonlinear behaviour characterized by low stiffness at small deformations. Furthermore, we find that the mechanical response of liposomes is influenced by their size. Additionally, we observe that the presence of adhesion energy contributes to the generation of negative tip forces upon initial contact.

Název v anglickém jazyce

NONLINEAR CELL DEFORMATION MODEL

Popis výsledku anglicky

Cytoskeletal mechanics is a field that heavily relies on mathematical models to interpret experimental data related to forces and deformations. In this paper, we present a novel mathematical model designed specifically for analysing the mechanical properties of liposomes, which serve as model systems for studying biological membranes. Our model takes into account various factors such as stretching, bending, and contact adhesion during atomic force microscopy (AFM) indentation using a spherical tip. By applying our model to liposomes, we demonstrate that these structures exhibit nonlinear behaviour characterized by low stiffness at small deformations. Furthermore, we find that the mechanical response of liposomes is influenced by their size. Additionally, we observe that the presence of adhesion energy contributes to the generation of negative tip forces upon initial contact.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Strojnícky časopis

ISSN

0039-2472

e-ISSN

2450-5471

Svazek periodika

2023

Číslo periodika v rámci svazku

november

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

9

Strana od-do

—

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85179053135