Mechanical Properties of Collagen-Poly-lactide/caprolactone Composite for Pulmonary Artery Banding

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F24%3A00369563" target="_blank" >RIV/68407700:21220/24:00369563 - isvavai.cz</a>

Výsledek na webu

<a href="http://ean61.kamasi.sk/EAN2023-Proceedings.zip" target="_blank" >http://ean61.kamasi.sk/EAN2023-Proceedings.zip</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Mechanical Properties of Collagen-Poly-lactide/caprolactone Composite for Pulmonary Artery Banding

Popis výsledku v původním jazyce

Pulmonary artery banding is a surgical procedure used in neonates to induce a mechanobiological response, leading to natural repair of certain congenital heart defects. Current banding methods involve a two-step procedure that requires the use of a non-absorbable material, necessitating surgical removal after a specific period of time. The objective of our project is to develop a banding material for pulmonary artery banding that eliminates the need for surgical removal in the second step by enabling resorption. In this study, we compare the mechanical properties of a composite banding material consisting of a copolymer of caprolactone (PCL) and lactide acid (PLA) used as reinforcement in a collagen matrix (COLL) with a commercially available banding material from W. L. GORE. Through uniaxial tensile testing, we demonstrate that our COLL-PLCL banding material exhibits greater compliance compared to GORE materials while maintaining sufficient strain at failure.

Název v anglickém jazyce

Mechanical Properties of Collagen-Poly-lactide/caprolactone Composite for Pulmonary Artery Banding

Popis výsledku anglicky

Pulmonary artery banding is a surgical procedure used in neonates to induce a mechanobiological response, leading to natural repair of certain congenital heart defects. Current banding methods involve a two-step procedure that requires the use of a non-absorbable material, necessitating surgical removal after a specific period of time. The objective of our project is to develop a banding material for pulmonary artery banding that eliminates the need for surgical removal in the second step by enabling resorption. In this study, we compare the mechanical properties of a composite banding material consisting of a copolymer of caprolactone (PCL) and lactide acid (PLA) used as reinforcement in a collagen matrix (COLL) with a commercially available banding material from W. L. GORE. Through uniaxial tensile testing, we demonstrate that our COLL-PLCL banding material exhibits greater compliance compared to GORE materials while maintaining sufficient strain at failure.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/NU20-02-00368" target="_blank" >NU20-02-00368: Biomechanicky definované vstřebatelné materiály pro kardiovaskulární chirurgii</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Experimental Stress Analysis 2023 Proceedings of Full Papers

ISBN

978-80-553-3677-0

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

125-129

Název nakladatele

Technical University of Košice

Místo vydání

Košice

Místo konání akce

Košice

Datum konání akce

6. 6. 2023

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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