Detekce korových oscilací vybuzených SCS pomocí výkonové spektrální hustoty

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F07%3A03135444" target="_blank" >RIV/68407700:21230/07:03135444 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density

Popis výsledku v původním jazyce

Chronic, intractable pain of lower back and lower extremity might develop as the result of unsuccessful surgery of back. This state called failed-back surgery syndrome cannot be effectively treated by pharmacotherapy. Electric stimulation of the dorsal spinal cord (SCS) is applied to relieve the pain. According to the medical hypothesis, oscillatory activity, which might be related to the analgesic effects, may occur in the cortex during the stimulation. To confirm the presence of the SCS induced oscillations, a new method of detection was designed. The analysis of EEG data was performed using power spectral density, confidence intervals, visualization and group statistic for its verification. Parameters of the method were experimentally optimized to maximize its reliability. During ongoing SCS, statistically significant changes were detected and localized at the stimulation frequency and/or its subharmonic or upper harmonic over central midline electrodes in eight patients.

Název v anglickém jazyce

Detection of Cortical Oscillations Induced by SCS Using Power Spectral Density

Popis výsledku anglicky

Chronic, intractable pain of lower back and lower extremity might develop as the result of unsuccessful surgery of back. This state called failed-back surgery syndrome cannot be effectively treated by pharmacotherapy. Electric stimulation of the dorsal spinal cord (SCS) is applied to relieve the pain. According to the medical hypothesis, oscillatory activity, which might be related to the analgesic effects, may occur in the cortex during the stimulation. To confirm the presence of the SCS induced oscillations, a new method of detection was designed. The analysis of EEG data was performed using power spectral density, confidence intervals, visualization and group statistic for its verification. Parameters of the method were experimentally optimized to maximize its reliability. During ongoing SCS, statistically significant changes were detected and localized at the stimulation frequency and/or its subharmonic or upper harmonic over central midline electrodes in eight patients.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JA - Elektronika a optoelektronika, elektrotechnika

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Radioengineering

ISSN

1210-2512

e-ISSN

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Svazek periodika

16

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

38-45

Kód UT WoS článku

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EID výsledku v databázi Scopus

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