Acoustic evaluation of nasality in cerebellar syndromes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F17%3A00318073" target="_blank" >RIV/68407700:21230/17:00318073 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.isca-speech.org/archive/Interspeech_2017/abstracts/0381.html" target="_blank" >http://www.isca-speech.org/archive/Interspeech_2017/abstracts/0381.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21437/Interspeech.2017-381" target="_blank" >10.21437/Interspeech.2017-381</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acoustic evaluation of nasality in cerebellar syndromes

Popis výsledku v původním jazyce

Although previous studies have reported the occurrence of velopharyngeal incompetence connected with ataxic dysarthria, there is a lack of evidence related to nasality assessment in cerebellar disorders. This is partly due to the limited reliability of challenging analyses and partly due to nasality being a less pronounced manifestation of ataxic dysarthria. Therefore, we employed 1/3-octave spectra analysis as an objective measurement of nasality disturbances. We analyzed 20 subjects with multiple system atrophy (MSA), 13 subjects with cerebellar ataxia (CA), 20 subjects with multiple sclerosis (MS) and 20 healthy (HC) speakers. Although we did not detect the presence of hypernasality, our results showed increased nasality fluctuation in 65% of MSA, 43% of CA and 30% of MS subjects compared to 15% of HC speakers, suggesting inconsistent velopharyngeal motor control. Furthermore, we found a statistically significant difference between MSA and HC participants (p<0.001), and significant correlation between the natural history cerebellar subscore and neuroprotection in Parkinson plus syndromes - Parkinson plus scale and nasality fluctuations in MSA (r=0.51, p<0.05). In conclusion, acoustic analysis showed an increased presence of abnormal nasality fluctuations in all ataxic groups and revealed that nasality fluctuation is associated with distortion of cerebellar functions.

Název v anglickém jazyce

Acoustic evaluation of nasality in cerebellar syndromes

Popis výsledku anglicky

Although previous studies have reported the occurrence of velopharyngeal incompetence connected with ataxic dysarthria, there is a lack of evidence related to nasality assessment in cerebellar disorders. This is partly due to the limited reliability of challenging analyses and partly due to nasality being a less pronounced manifestation of ataxic dysarthria. Therefore, we employed 1/3-octave spectra analysis as an objective measurement of nasality disturbances. We analyzed 20 subjects with multiple system atrophy (MSA), 13 subjects with cerebellar ataxia (CA), 20 subjects with multiple sclerosis (MS) and 20 healthy (HC) speakers. Although we did not detect the presence of hypernasality, our results showed increased nasality fluctuation in 65% of MSA, 43% of CA and 30% of MS subjects compared to 15% of HC speakers, suggesting inconsistent velopharyngeal motor control. Furthermore, we found a statistically significant difference between MSA and HC participants (p<0.001), and significant correlation between the natural history cerebellar subscore and neuroprotection in Parkinson plus syndromes - Parkinson plus scale and nasality fluctuations in MSA (r=0.51, p<0.05). In conclusion, acoustic analysis showed an increased presence of abnormal nasality fluctuations in all ataxic groups and revealed that nasality fluctuation is associated with distortion of cerebellar functions.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

INTERSPEECH 2017

ISBN

—

ISSN

2308-457X

e-ISSN

1990-9772

Počet stran výsledku

5

Strana od-do

3132-3136

Název nakladatele

ISCA - International Speech Communication Association

Místo vydání

Bochum

Místo konání akce

Stockholm

Datum konání akce

20. 8. 2017

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

—