SERS sensor based on functionalized gold grating as a platform for the signal improvement on a portable Raman spectrometer

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

SERS sensor based on functionalized gold grating as a platform for the signal improvement on a portable Raman spectrometer

Popis výsledku v původním jazyce

We proposed a SERS-based universal sensor system, consisting of the highly-ordered gold grating, which enables to detect analytes on a molecular level and provide high reproducibility of response and a covalently grafted layer of organic functional groups (OFGs). OFGs serve as a capturing agent, enhancing the affinity to the analyte, what facilitates preconcentration of the analyte on the sensor surface and provide excellent selectivity. By proposed concept SERS sensor system can be functionalized by various ligands- for the rapid determination of metal ions, azo-dyes, cholesterol markers, DNA complementarity, trapping of pesticides and other contaminants, detection of specific markers of cancer cells, free radicals, enantiomeric excess in the validation of drugs. Suggested functionalized gold gratings demonstrate principal advantages for efficient SERS detection: expressivity, sensitivity, selectivity, pretreatment free procedure, and reproducibility.

Název v anglickém jazyce

SERS sensor based on functionalized gold grating as a platform for the signal improvement on a portable Raman spectrometer

Popis výsledku anglicky

We proposed a SERS-based universal sensor system, consisting of the highly-ordered gold grating, which enables to detect analytes on a molecular level and provide high reproducibility of response and a covalently grafted layer of organic functional groups (OFGs). OFGs serve as a capturing agent, enhancing the affinity to the analyte, what facilitates preconcentration of the analyte on the sensor surface and provide excellent selectivity. By proposed concept SERS sensor system can be functionalized by various ligands- for the rapid determination of metal ions, azo-dyes, cholesterol markers, DNA complementarity, trapping of pesticides and other contaminants, detection of specific markers of cancer cells, free radicals, enantiomeric excess in the validation of drugs. Suggested functionalized gold gratings demonstrate principal advantages for efficient SERS detection: expressivity, sensitivity, selectivity, pretreatment free procedure, and reproducibility.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10403 - Physical chemistry

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

29th Conference and Exhibition on OPTICAL COMMUNICATIONS 2018

ISBN

978-80-86742-50-2

ISSN

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e-ISSN

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Počet stran výsledku

46

Strana od-do

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Název nakladatele

Zeithamlová Milena Ing. - Agentura Action M

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

25. 10. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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