Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F19%3A00333023" target="_blank" >RIV/68407700:21230/19:00333023 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1002/mp.13704" target="_blank" >https://doi.org/10.1002/mp.13704</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mp.13704" target="_blank" >10.1002/mp.13704</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models

Popis výsledku v původním jazyce

Computational models of microwave tissue ablation are widely used to guide the development of ablation devices, and are increasingly being used for the development of treatment planning and monitoring platforms. Knowledge of temperature-dependent dielectric properties of lung tissue is essential for accurate modeling of microwave ablation (MWA) of the lung. We employed the open-ended coaxial probe method, coupled with a custom tissue heating apparatus, to measure dielectric properties of ex vivo porcine and bovine lung tissue at temperatures ranging between 31 and 150 urn:x-wiley:00942405:media:mp13704:mp13704-math-0007C, over the frequency range 500 MHz to 6 GHz. Furthermore, we employed numerical optimization techniques to provide parametric models for characterizing the broadband temperature-dependent dielectric properties of tissue, and their variability across tissue samples, suitable for use in computational models of microwave tissue ablation. Rapid decreases in both relative permittivity and effective conductivity were observed in the temperature range from 94 to 108 urn:x-wiley:00942405:media:mp13704:mp13704-math-0008C. Over the measured frequency range, both relative permittivity and effective conductivity were suitably modeled by piecewise linear functions [root mean square error (RMSE) = 1.0952 for permittivity and 0.0650 S/m for conductivity]. Detailed characterization of the variability in lung tissue properties was provided to enable uncertainty quantification of models of MWA. The reported dielectric properties of lung tissue, and parametric models which also capture their distribution, will aid the development of computational models of microwave lung ablation.

Název v anglickém jazyce

Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models

Popis výsledku anglicky

Computational models of microwave tissue ablation are widely used to guide the development of ablation devices, and are increasingly being used for the development of treatment planning and monitoring platforms. Knowledge of temperature-dependent dielectric properties of lung tissue is essential for accurate modeling of microwave ablation (MWA) of the lung. We employed the open-ended coaxial probe method, coupled with a custom tissue heating apparatus, to measure dielectric properties of ex vivo porcine and bovine lung tissue at temperatures ranging between 31 and 150 urn:x-wiley:00942405:media:mp13704:mp13704-math-0007C, over the frequency range 500 MHz to 6 GHz. Furthermore, we employed numerical optimization techniques to provide parametric models for characterizing the broadband temperature-dependent dielectric properties of tissue, and their variability across tissue samples, suitable for use in computational models of microwave tissue ablation. Rapid decreases in both relative permittivity and effective conductivity were observed in the temperature range from 94 to 108 urn:x-wiley:00942405:media:mp13704:mp13704-math-0008C. Over the measured frequency range, both relative permittivity and effective conductivity were suitably modeled by piecewise linear functions [root mean square error (RMSE) = 1.0952 for permittivity and 0.0650 S/m for conductivity]. Detailed characterization of the variability in lung tissue properties was provided to enable uncertainty quantification of models of MWA. The reported dielectric properties of lung tissue, and parametric models which also capture their distribution, will aid the development of computational models of microwave lung ablation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medical Physics

ISSN

0094-2405

e-ISSN

2473-4209

Svazek periodika

—

Číslo periodika v rámci svazku

July

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

4291-4303

Kód UT WoS článku

000481397500001

EID výsledku v databázi Scopus

2-s2.0-85070292833