Which aspects of motor speech disorder are captured by Mel Frequency Cepstral Coefficients? Evidence from the change in STN-DBS conditions in Parkinson's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F23%3A00368518" target="_blank" >RIV/68407700:21230/23:00368518 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/23:43927330

Výsledek na webu

<a href="https://doi.org/10.21437/Interspeech.2023-1744" target="_blank" >https://doi.org/10.21437/Interspeech.2023-1744</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21437/Interspeech.2023-1744" target="_blank" >10.21437/Interspeech.2023-1744</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Which aspects of motor speech disorder are captured by Mel Frequency Cepstral Coefficients? Evidence from the change in STN-DBS conditions in Parkinson's disease

Popis výsledku v původním jazyce

One of the most popular speech parametrizations for dysarthria has been Mel Frequency Cepstral Coefficients (MFCCs). Although the MFCCs ability to capture vocal tract characteristics is known, the reflected dysarthria aspects are primarily undisclosed. Thus, we investigated the relationship between key acoustic variables in Parkinson's disease (PD) and the MFCCs. 23 PD patients were recruited with ON and OFF conditions of Deep Brain Stimulation of the Subthalamic Nucleus (STN-DBS) and examined via a reading passage. The changes in dysarthria aspects were compared to changes in a global MFCC measure and individual MFCCs. A similarity was found in 2nd to 3rd MFCCs changes and voice quality. Changes in 4th to 9th MFCCs reflected articulation clarity. The global MFCC parameter outperformed individual MFCCs and acoustical measures in capturing STN-DBS conditions changes. The findings may assist in interpreting outcomes from clinical trials and improve the monitoring of disease progression.

Název v anglickém jazyce

Which aspects of motor speech disorder are captured by Mel Frequency Cepstral Coefficients? Evidence from the change in STN-DBS conditions in Parkinson's disease

Popis výsledku anglicky

One of the most popular speech parametrizations for dysarthria has been Mel Frequency Cepstral Coefficients (MFCCs). Although the MFCCs ability to capture vocal tract characteristics is known, the reflected dysarthria aspects are primarily undisclosed. Thus, we investigated the relationship between key acoustic variables in Parkinson's disease (PD) and the MFCCs. 23 PD patients were recruited with ON and OFF conditions of Deep Brain Stimulation of the Subthalamic Nucleus (STN-DBS) and examined via a reading passage. The changes in dysarthria aspects were compared to changes in a global MFCC measure and individual MFCCs. A similarity was found in 2nd to 3rd MFCCs changes and voice quality. Changes in 4th to 9th MFCCs reflected articulation clarity. The global MFCC parameter outperformed individual MFCCs and acoustical measures in capturing STN-DBS conditions changes. The findings may assist in interpreting outcomes from clinical trials and improve the monitoring of disease progression.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH 2023

ISBN

—

ISSN

2308-457X

e-ISSN

—

Počet stran výsledku

5

Strana od-do

5027-5031

Název nakladatele

ISCA - International Speech Communication Association

Místo vydání

Bochum

Místo konání akce

Dublin

Datum konání akce

21. 8. 2023

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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