Feasibility study of direct cyclotron production of 227-Th

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F13%3A00214680" target="_blank" >RIV/68407700:21340/13:00214680 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Feasibility study of direct cyclotron production of 227-Th

Popis výsledku v původním jazyce

Aim Alpha emitting radiometals are promising tools for cancer treatment. One of them is 223Ra (half-life of 11.4 days) together with its mother nuclide, 227Th (half-life of 18.7 days).These nuclides can be obtained from 227Ac/227Th/223Ra generator produced via 226Ra(n,?)227Ra/227Ac reaction using nuclear reactor. This fact puts, however, high requirements on radiation stability of such a generator. Aim of this study was to develop alternative method for direct cyclotron production of 227Th via 226Ra(?,3n) reaction. Methods Cross-sections of the 226Ra(?,3n) reaction were adopted from TENDL-2012 library based on TALYS nuclear model code. Using these data, thick target yields of this reaction were calculated. Experimental verification of the predicted values was performed on a U-120M isochronous cyclotron of the Nuclear Physics Institute of the Academy of Science of the Czech Republic by irradiating single thin 226Ra targets. The targets were then analysed using alpha and gamma spectromet

Název v anglickém jazyce

Feasibility study of direct cyclotron production of 227-Th

Popis výsledku anglicky

Aim Alpha emitting radiometals are promising tools for cancer treatment. One of them is 223Ra (half-life of 11.4 days) together with its mother nuclide, 227Th (half-life of 18.7 days).These nuclides can be obtained from 227Ac/227Th/223Ra generator produced via 226Ra(n,?)227Ra/227Ac reaction using nuclear reactor. This fact puts, however, high requirements on radiation stability of such a generator. Aim of this study was to develop alternative method for direct cyclotron production of 227Th via 226Ra(?,3n) reaction. Methods Cross-sections of the 226Ra(?,3n) reaction were adopted from TENDL-2012 library based on TALYS nuclear model code. Using these data, thick target yields of this reaction were calculated. Experimental verification of the predicted values was performed on a U-120M isochronous cyclotron of the Nuclear Physics Institute of the Academy of Science of the Czech Republic by irradiating single thin 226Ra targets. The targets were then analysed using alpha and gamma spectromet

Druh

O - Ostatní výsledky

CEP obor

CH - Jaderná a kvantová chemie, fotochemie

OECD FORD obor

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Projekt

<a href="/cs/project/LK21310" target="_blank" >LK21310: Studium transmutace a separace produktů ozařování Ra-226</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů