Preparation of 223Ra by neutron irradiation of 226Ra

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F14%3A00218487" target="_blank" >RIV/68407700:21340/14:00218487 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Preparation of 223Ra by neutron irradiation of 226Ra

Popis výsledku v původním jazyce

Radium-223 is prospective alpha-emmiting therapeutic radionuclide for targeted radionuclide therapy. Although Ra-223 is formed naturally by the decay of U-235, for practical reasons its preparation involves neutron irradiation of Ra-226. The decay of Ra-227 leads to Ac-227, which decays to Th-227 and Ra-223 subsequently. Ra-226 as a decay product of U-238 is generally available in multigram quantities (mainly historical stock). Main purpose of this study was to experimentally and theoretically evaluateand verify available literature data on productionof Ra-223. According to dates obtained from gamma spectra, the yield of this irradiation and cross sections were calculated. Radium-226 sample was flame-sealed in a quartz ampoule and irradiated for 11,7days in a neutron flow. The yield of Ra-223 and other products were determined several weeks after EOB by evaluation of gamma and alfa spectra. Less than one month after irradiation Ra-223, Pb-212, Bi-212, Tl-208 peaks can be found on gam

Název v anglickém jazyce

Preparation of 223Ra by neutron irradiation of 226Ra

Popis výsledku anglicky

Radium-223 is prospective alpha-emmiting therapeutic radionuclide for targeted radionuclide therapy. Although Ra-223 is formed naturally by the decay of U-235, for practical reasons its preparation involves neutron irradiation of Ra-226. The decay of Ra-227 leads to Ac-227, which decays to Th-227 and Ra-223 subsequently. Ra-226 as a decay product of U-238 is generally available in multigram quantities (mainly historical stock). Main purpose of this study was to experimentally and theoretically evaluateand verify available literature data on productionof Ra-223. According to dates obtained from gamma spectra, the yield of this irradiation and cross sections were calculated. Radium-226 sample was flame-sealed in a quartz ampoule and irradiated for 11,7days in a neutron flow. The yield of Ra-223 and other products were determined several weeks after EOB by evaluation of gamma and alfa spectra. Less than one month after irradiation Ra-223, Pb-212, Bi-212, Tl-208 peaks can be found on gam

Druh

O - Ostatní výsledky

CEP obor

CH - Jaderná a kvantová chemie, fotochemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů