Distribution of the pressure and tidal volume in multicompartment model of the lung during mechanical ventilation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F14%3A00310147" target="_blank" >RIV/68407700:21460/14:00310147 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1515/bmt-2014-4414" target="_blank" >http://dx.doi.org/10.1515/bmt-2014-4414</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/bmt-2014-4414" target="_blank" >10.1515/bmt-2014-4414</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Distribution of the pressure and tidal volume in multicompartment model of the lung during mechanical ventilation

Popis výsledku v původním jazyce

Introduction Regional changes of mechanical properties of lung tissue can be a cause of lung tissue injury by ventilator known as ventilator induced lung injury. The aim of this paper is to study the intrapulmonary parameters in the model of the respiratory system that was designed according to the morphometrical description of the lungs. Methods The model of respiratory system was designed for this study according to Horsfield morphological description. Central airways were modeled in the SolidWorks programme and printed on the 3D printer Objet 24 Pro (Stratasys, USA). Alveolar space of the model was divided into the five compartments according to the Horsfield model of the lungs. The alveolar space was modeled by glass demijohns. The model was prepared to allow measuring pressures and tidal volumes in each compartment. Model was ventilated by mechanical convention ventilator Avea (CareFusion, USA). The volume of the air was measured by respiratory monitory Florian (hot-wire anemometer). Measure d data were processed by LabVIEW programme. Parabolic resistor was placed into the entry of alveolar space as simulation of airway obstruction and VT and pressure was measured. Results Conducted measurement on the model showed different effect of resistance and compliance upon the distribution of pressure and tidal volume into the compartments. The changed resistance has only small effect upon the delivery of tidal volume whereas the compliance of the compartment significantly affects the tidal volume. Time trend of the pressure is similar in all compartments with different compliance and also the effect of the changed resistance was only slight.

Název v anglickém jazyce

Distribution of the pressure and tidal volume in multicompartment model of the lung during mechanical ventilation

Popis výsledku anglicky

Introduction Regional changes of mechanical properties of lung tissue can be a cause of lung tissue injury by ventilator known as ventilator induced lung injury. The aim of this paper is to study the intrapulmonary parameters in the model of the respiratory system that was designed according to the morphometrical description of the lungs. Methods The model of respiratory system was designed for this study according to Horsfield morphological description. Central airways were modeled in the SolidWorks programme and printed on the 3D printer Objet 24 Pro (Stratasys, USA). Alveolar space of the model was divided into the five compartments according to the Horsfield model of the lungs. The alveolar space was modeled by glass demijohns. The model was prepared to allow measuring pressures and tidal volumes in each compartment. Model was ventilated by mechanical convention ventilator Avea (CareFusion, USA). The volume of the air was measured by respiratory monitory Florian (hot-wire anemometer). Measure d data were processed by LabVIEW programme. Parabolic resistor was placed into the entry of alveolar space as simulation of airway obstruction and VT and pressure was measured. Results Conducted measurement on the model showed different effect of resistance and compliance upon the distribution of pressure and tidal volume into the compartments. The changed resistance has only small effect upon the delivery of tidal volume whereas the compliance of the compartment significantly affects the tidal volume. Time trend of the pressure is similar in all compartments with different compliance and also the effect of the changed resistance was only slight.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FS - Lékařská zařízení, přístroje a vybavení

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Engineering - Biomedizinische Technik

ISSN

0013-5585

e-ISSN

—

Svazek periodika

59

Číslo periodika v rámci svazku

s1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

1

Strana od-do

"S992"-"S992"

Kód UT WoS článku

000350405700426

EID výsledku v databázi Scopus

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