Experimental analysis of cellular membrane mechanical properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F17%3A00316566" target="_blank" >RIV/68407700:21460/17:00316566 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Experimental analysis of cellular membrane mechanical properties

Popis výsledku v původním jazyce

The study of mechanical processes at the cellular level is currently an essential topic. The study of cell-environment interaction can reveal the possibilities of using nanoparticles in biomedicine. The work is focused at creating a methology for measuring of mechanical properties on living cells using atomic force microscopy and force spectroscopy. So far we have been working on inanimate cells in phosphate-buffered saline. We work with mouse fibroblasts labeled CT26.WT from a colon. This work presents the achieved results of the successful first phase of using atomic force microscopy for cell measurements. The measurement method by atomic force microscopy on living cells is necessary for simple and fast acquisition of required information such as nano-hardness and adhesion of a membrane.

Název v anglickém jazyce

Experimental analysis of cellular membrane mechanical properties

Popis výsledku anglicky

The study of mechanical processes at the cellular level is currently an essential topic. The study of cell-environment interaction can reveal the possibilities of using nanoparticles in biomedicine. The work is focused at creating a methology for measuring of mechanical properties on living cells using atomic force microscopy and force spectroscopy. So far we have been working on inanimate cells in phosphate-buffered saline. We work with mouse fibroblasts labeled CT26.WT from a colon. This work presents the achieved results of the successful first phase of using atomic force microscopy for cell measurements. The measurement method by atomic force microscopy on living cells is necessary for simple and fast acquisition of required information such as nano-hardness and adhesion of a membrane.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů