Experimental analysis of cellular membrane mechanical properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F19%3A00326353" target="_blank" >RIV/68407700:21460/19:00326353 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-981-10-9038-7_138" target="_blank" >http://dx.doi.org/10.1007/978-981-10-9038-7_138</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-10-9038-7_138" target="_blank" >10.1007/978-981-10-9038-7_138</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Experimental analysis of cellular membrane mechanical properties

Popis výsledku v původním jazyce

The study of cell-environment can reveal the possibilities of using nanoparticles in biomedicine. The condition of the cell membrane reflects the mood of whole cell. The membranes as the outer envelope of the cell have a semi-fluid character, and the proteins and lipid molecules are in constant motion. Our aim is to develop methodology for measuring of cell mechanical properties. Atomic force microscopy and force spectroscopy were selected for contact between a tip of cantilever and a cell. This work presents the results of comparison using different tips of cantilevers and verification on several types of cells. Dependence between Young’s modulus of a cell membrane and surface attachment is next part of this work. Different surfaces are creating by coating of glass. Working with living cells claims specific approach in all parts of the research. The results compare the properties of the same cells on different surfaces.

Název v anglickém jazyce

Experimental analysis of cellular membrane mechanical properties

Popis výsledku anglicky

The study of cell-environment can reveal the possibilities of using nanoparticles in biomedicine. The condition of the cell membrane reflects the mood of whole cell. The membranes as the outer envelope of the cell have a semi-fluid character, and the proteins and lipid molecules are in constant motion. Our aim is to develop methodology for measuring of cell mechanical properties. Atomic force microscopy and force spectroscopy were selected for contact between a tip of cantilever and a cell. This work presents the results of comparison using different tips of cantilevers and verification on several types of cells. Dependence between Young’s modulus of a cell membrane and surface attachment is next part of this work. Different surfaces are creating by coating of glass. Working with living cells claims specific approach in all parts of the research. The results compare the properties of the same cells on different surfaces.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30404 - Biomaterials (as related to medical implants, devices, sensors)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

World Congress on Medical Physics and Biomedical Engineering 2018

ISBN

978-981-10-9038-7

ISSN

—

e-ISSN

1680-0737

Počet stran výsledku

5

Strana od-do

745-749

Název nakladatele

Springer Nature Singapore Pte Ltd.

Místo vydání

—

Místo konání akce

Prague

Datum konání akce

3. 6. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000449742700138