Antibacterial coatings for biomedical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F18%3A00326986" target="_blank" >RIV/68407700:21460/18:00326986 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-94-024-1298-7_46" target="_blank" >http://dx.doi.org/10.1007/978-94-024-1298-7_46</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-94-024-1298-7_46" target="_blank" >10.1007/978-94-024-1298-7_46</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antibacterial coatings for biomedical applications

Popis výsledku v původním jazyce

Diamond like carbon (DLC) and Ag-doped DLC (Ag-DLC)films were prepared by dual pulsed laser deposition using graphite and silver targets and twoKrF excimer lasers. The silver concentration in thefilms was varied from 1.1 to9.3 at. %. The surface topography was analysed by atomic force microscopy. Thepure DLC was very smooth, but the roughness increased with rising silver content.Ethylene glycol, diiodomethane and deionized water were used to measure contactangles (CA). The measurements for water showed that the CA of Ag-DLC films (78–98) was higher than that of the DLC film (77). In order to understand theinfluence of incorporated Ag on the wettability, the surface energy and the proteinadsorption as an indirect measure of the hemocompatibility were calculated. Thesurface energy of DLC and Ag-DLC films was same. The hemocompatibility wasexamined by the adsorption ratio of albumin/ fibrinogen as an indirect method andimproved with the increase of the Ag concentration. The antibacterial activity of thefilms were evaluated by bacterial eradication tests with Staphylococcus aureusandPseudomonas aeruginosaat different incubation times. DLC and Ag-DLCfilmsdemonstrated good results againstStaphylococcus aureus andPseudomonasaeruginosa, meaning that DLC and Ag-DLC can be useful to produce coatingswith antibacterial properties for biomedical devices such as sensors.

Název v anglickém jazyce

Antibacterial coatings for biomedical applications

Popis výsledku anglicky

Diamond like carbon (DLC) and Ag-doped DLC (Ag-DLC)films were prepared by dual pulsed laser deposition using graphite and silver targets and twoKrF excimer lasers. The silver concentration in thefilms was varied from 1.1 to9.3 at. %. The surface topography was analysed by atomic force microscopy. Thepure DLC was very smooth, but the roughness increased with rising silver content.Ethylene glycol, diiodomethane and deionized water were used to measure contactangles (CA). The measurements for water showed that the CA of Ag-DLC films (78–98) was higher than that of the DLC film (77). In order to understand theinfluence of incorporated Ag on the wettability, the surface energy and the proteinadsorption as an indirect measure of the hemocompatibility were calculated. Thesurface energy of DLC and Ag-DLC films was same. The hemocompatibility wasexamined by the adsorption ratio of albumin/ fibrinogen as an indirect method andimproved with the increase of the Ag concentration. The antibacterial activity of thefilms were evaluated by bacterial eradication tests with Staphylococcus aureusandPseudomonas aeruginosaat different incubation times. DLC and Ag-DLCfilmsdemonstrated good results againstStaphylococcus aureus andPseudomonasaeruginosa, meaning that DLC and Ag-DLC can be useful to produce coatingswith antibacterial properties for biomedical devices such as sensors.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Advanced Nanotechnologies for Detection and Defence against CBRN Agents

ISBN

978-94-024-1516-2

Počet stran výsledku

10

Strana od-do

467-476

Počet stran knihy

512

Název nakladatele

Springer Nature

Místo vydání

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Kód UT WoS kapitoly

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