Analysis of Left Ventricular Unloading by Double Lumen Arterial Cannula During ECMO Assessed by Mathematical Modeling

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F19%3A00321937" target="_blank" >RIV/68407700:21460/19:00321937 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.springer.com/gp/book/9789811090349" target="_blank" >https://www.springer.com/gp/book/9789811090349</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-10-9035-6_138" target="_blank" >10.1007/978-981-10-9035-6_138</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Analysis of Left Ventricular Unloading by Double Lumen Arterial Cannula During ECMO Assessed by Mathematical Modeling

Popis výsledku v původním jazyce

Extracorporeal membrane oxygenation is increasingly used for the therapy of the cardiogenic shock. However, it has been repeatedly shown that increased afterload associated with extracorporeal membrane oxygenation significantly deteriorates left ventricular performance. A number of approaches suggested how to deal with left ventricular unloading. Each of these methods requires extra interventions, which increase invasiveness of the method and thus does not correspond with current trends in the mini-invasive performance. Therefore, the development of a mini-invasive method of left heart decompression is a significant issue in extracorporeal membrane oxygenation therapy. The study presents an alternative mini-invasive method for the left ventricular unloading during extracorporeal membrane oxygenation. The draft of double lumen arterial cannula for left ventricular unloading during extracorporeal membrane oxygenation was created in AutoCAD software. The Modelica modeling language was used for modeling and simulations. The initial parameter values were derived from measurements on a female swine. Our simulation results indicate that drainage lumen of the presented double lumen arterial cannula for veno-arterial extracorporeal membrane oxygenation is capable of withdrawing 0.374 L/min during extracorporeal blood flow 1 L/min, 0.441 L/min during 2 L/min, 0.481 L/min during 3 L/min, 0.532 L/min during 4 L/min, 0.560 L/min during 5L/min. The double lumen arterial cannula presents an alternative and perspective solution. It is less invasive than the currently used methods for the left ventricle decompression during veno-arterial extracorporeal membrane oxygenation. The double lumen arterial cannula is capable of achieving left ventricle decompression and blood return while requiring only one single puncture.

Název v anglickém jazyce

Analysis of Left Ventricular Unloading by Double Lumen Arterial Cannula During ECMO Assessed by Mathematical Modeling

Popis výsledku anglicky

Extracorporeal membrane oxygenation is increasingly used for the therapy of the cardiogenic shock. However, it has been repeatedly shown that increased afterload associated with extracorporeal membrane oxygenation significantly deteriorates left ventricular performance. A number of approaches suggested how to deal with left ventricular unloading. Each of these methods requires extra interventions, which increase invasiveness of the method and thus does not correspond with current trends in the mini-invasive performance. Therefore, the development of a mini-invasive method of left heart decompression is a significant issue in extracorporeal membrane oxygenation therapy. The study presents an alternative mini-invasive method for the left ventricular unloading during extracorporeal membrane oxygenation. The draft of double lumen arterial cannula for left ventricular unloading during extracorporeal membrane oxygenation was created in AutoCAD software. The Modelica modeling language was used for modeling and simulations. The initial parameter values were derived from measurements on a female swine. Our simulation results indicate that drainage lumen of the presented double lumen arterial cannula for veno-arterial extracorporeal membrane oxygenation is capable of withdrawing 0.374 L/min during extracorporeal blood flow 1 L/min, 0.441 L/min during 2 L/min, 0.481 L/min during 3 L/min, 0.532 L/min during 4 L/min, 0.560 L/min during 5L/min. The double lumen arterial cannula presents an alternative and perspective solution. It is less invasive than the currently used methods for the left ventricle decompression during veno-arterial extracorporeal membrane oxygenation. The double lumen arterial cannula is capable of achieving left ventricle decompression and blood return while requiring only one single puncture.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

World Congress on Medical Physics and Biomedical Engineering 2018 (Vol. 1)

ISBN

978-981-10-9034-9

ISSN

1680-0737

e-ISSN

—

Počet stran výsledku

5

Strana od-do

749-753

Název nakladatele

Springer Nature Singapore Pte Ltd.

Místo vydání

—

Místo konání akce

Prague

Datum konání akce

3. 6. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000450908300138