Significant decrease of methemoglobin and carboxyhemoglobin during short-time hypoxic breathing experiment in simulated avalanche snow

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F22%3A00358029" target="_blank" >RIV/68407700:21460/22:00358029 - isvavai.cz</a>

Výsledek na webu

<a href="http://poseidon2.feld.cvut.cz/conf/poster/proceedings/POSTER_2022.pdf" target="_blank" >http://poseidon2.feld.cvut.cz/conf/poster/proceedings/POSTER_2022.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Significant decrease of methemoglobin and carboxyhemoglobin during short-time hypoxic breathing experiment in simulated avalanche snow

Popis výsledku v původním jazyce

Current modern pulse oximeters allow noninvasive monitoring of dysfunctional forms of hemoglobin. The concentrations of Methemoglobin (MetHb) and Carboxyhemoglobin (COHb) indicate the state of the organism, but the accuracy of the measurement of these parameters may be reduced during hypoxia. The aim of the study was to determine the effect of the decrease of peripheral oxygen saturation (SpO2) on measured concentrations of MetHb and COHb during short-time breathing experiments with simulated avalanche snow accompanied by a rapid onset of hypoxemia. Thirteen volunteers (age 22.4 ± 1.3 years, weight 78.1 ± 10.1 kg) underwent a breathing experiment into perlite as a surrogate of avalanche snow. Rapid onset of hypoxemia and hypercapnia occurred while MetHb, COHb, and SpO2 were measured continuously by a monitor of oxygenation Masimo Root (Masimo Corporation, Irwine, CA). On average, the measured MetHb concentration decreased to 50 % at the end of the breathing trial (lowest SpO2 values) compared to the stabilization phase. COHb concentrations were even three times lower than in the stabilization phase. Although the measured decrease in both parameters was significant, the authors speculate that it is caused by the decreased accuracy of detection system of pulse oximeter. SpO2 concentrations should also be considered when determining MetHb and COHb concentrations using pulse oximeter.

Název v anglickém jazyce

Significant decrease of methemoglobin and carboxyhemoglobin during short-time hypoxic breathing experiment in simulated avalanche snow

Popis výsledku anglicky

Current modern pulse oximeters allow noninvasive monitoring of dysfunctional forms of hemoglobin. The concentrations of Methemoglobin (MetHb) and Carboxyhemoglobin (COHb) indicate the state of the organism, but the accuracy of the measurement of these parameters may be reduced during hypoxia. The aim of the study was to determine the effect of the decrease of peripheral oxygen saturation (SpO2) on measured concentrations of MetHb and COHb during short-time breathing experiments with simulated avalanche snow accompanied by a rapid onset of hypoxemia. Thirteen volunteers (age 22.4 ± 1.3 years, weight 78.1 ± 10.1 kg) underwent a breathing experiment into perlite as a surrogate of avalanche snow. Rapid onset of hypoxemia and hypercapnia occurred while MetHb, COHb, and SpO2 were measured continuously by a monitor of oxygenation Masimo Root (Masimo Corporation, Irwine, CA). On average, the measured MetHb concentration decreased to 50 % at the end of the breathing trial (lowest SpO2 values) compared to the stabilization phase. COHb concentrations were even three times lower than in the stabilization phase. Although the measured decrease in both parameters was significant, the authors speculate that it is caused by the decreased accuracy of detection system of pulse oximeter. SpO2 concentrations should also be considered when determining MetHb and COHb concentrations using pulse oximeter.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20601 - Medical engineering

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the International Student Scientific Conference Poster – 26/2022

ISBN

978-80-01-06992-9

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

52-55

Název nakladatele

Fakulta elektrotechnická

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

12. 5. 2022

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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