Estimation of Radiation Exposure of Family Members during Home Care of a Patient after Radionuclide Therapy Using 177Lu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F22%3A00359958" target="_blank" >RIV/68407700:21460/22:00359958 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/content/pdf/10.1007/s00259-022-05924-4.pdf" target="_blank" >https://link.springer.com/content/pdf/10.1007/s00259-022-05924-4.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Estimation of Radiation Exposure of Family Members during Home Care of a Patient after Radionuclide Therapy Using 177Lu

Popis výsledku v původním jazyce

The radionuclide 177Lu is used in therapy to treat selected groups of tumours. This treatment is usually carried out during the patient’s hospitalization. However, under certain conditions, it is possible to administer 177Lu on an outpatient basis. After the patient is released to home care, it is necessary to follow the relevant principles of radiation protection and eliminate the unnecessary radiation burden of people living in the household with the patient. The paper aims to estimate the exposure of family members during home care of the patient after radionuclide therapy. From May 2021 to the end of March 2022, 29 measurements were performed at a selected Nuclear Medicine Department (NMD) in people taking care of 21 patients after their treatment with a 177Lu-labeled radiopharmaceutical. After the patient was released to home care, one person living with the patient in the same household was equipped with a personal electronic dosimeter. This person was monitored by a personal dosimeter calibrated in terms of the personal dose equivalent of Hp(10). The dosimeter was carried for one week, and the reading was taken every morning. The time this person spent with the patient during the day was also taken into account. In selected situations where the patient was close to a family member (transport by car, administration of drugs to a lying patient, etc.), the dose equivalent rate of the patient’s caregiver was calculated using MCNP simulation. The average time spent with the patient during the week after the first therapeutic dose was approximately 14 hours, and the length of stay for repeated therapies was longer (average 32 hours), but caregivers already had more experience in keeping a sufficient distance from the patient. Based on measurements and using the Monte Carlo simulations, the average radiation exposure of the caregiver at home for 1 week was estimated to be approximately 18 μSv. In the case of outpatient therapy, it is necessary to give sufficiently detailed.

Název v anglickém jazyce

Estimation of Radiation Exposure of Family Members during Home Care of a Patient after Radionuclide Therapy Using 177Lu

Popis výsledku anglicky

The radionuclide 177Lu is used in therapy to treat selected groups of tumours. This treatment is usually carried out during the patient’s hospitalization. However, under certain conditions, it is possible to administer 177Lu on an outpatient basis. After the patient is released to home care, it is necessary to follow the relevant principles of radiation protection and eliminate the unnecessary radiation burden of people living in the household with the patient. The paper aims to estimate the exposure of family members during home care of the patient after radionuclide therapy. From May 2021 to the end of March 2022, 29 measurements were performed at a selected Nuclear Medicine Department (NMD) in people taking care of 21 patients after their treatment with a 177Lu-labeled radiopharmaceutical. After the patient was released to home care, one person living with the patient in the same household was equipped with a personal electronic dosimeter. This person was monitored by a personal dosimeter calibrated in terms of the personal dose equivalent of Hp(10). The dosimeter was carried for one week, and the reading was taken every morning. The time this person spent with the patient during the day was also taken into account. In selected situations where the patient was close to a family member (transport by car, administration of drugs to a lying patient, etc.), the dose equivalent rate of the patient’s caregiver was calculated using MCNP simulation. The average time spent with the patient during the week after the first therapeutic dose was approximately 14 hours, and the length of stay for repeated therapies was longer (average 32 hours), but caregivers already had more experience in keeping a sufficient distance from the patient. Based on measurements and using the Monte Carlo simulations, the average radiation exposure of the caregiver at home for 1 week was estimated to be approximately 18 μSv. In the case of outpatient therapy, it is necessary to give sufficiently detailed.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10304 - Nuclear physics

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů