Flow determination in pulmonary arteries using transluminal gradient

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F22%3A00361271" target="_blank" >RIV/68407700:21460/22:00361271 - isvavai.cz</a>

Výsledek na webu

<a href="http://imbm.fbmi.cvut.cz/soubory/Sborniky/IMBM%202022" target="_blank" >http://imbm.fbmi.cvut.cz/soubory/Sborniky/IMBM%202022</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Flow determination in pulmonary arteries using transluminal gradient

Popis výsledku v původním jazyce

Computed tomography pulmonary angiography (CTPA) is a strong tool for estimating pulmonary arteries morphology. Nevertheless, it cannot supply quantitative information about hemodynamics. Creating patient-specific models is a novel method of diagnosing, which allows to assess the flow and pressure behaviour in the stenosed vessels in patients with chronical thromboembolic pulmonary hypertension. 3D model of pulmonary arteries is extracted from the set of CTPA image data and the 3D point cloud is exported. Since each point is defined with 3 spatial coordinates and Hounsfield unit respectively it is possible to follow the change of contrast medium concentration along the pulmonary arteries up to the periphery. Absolute value of flow rate in artery directly from the CT scan is calculated using only several parameters, such as average cross-sectional area of the vessel, distance from the ostium and contrast bolus duration. Transluminal gradient method of flow rate determination is used to obtain outlet boundary conditions for further blood flow simulation. In comparison with boundary condition calculation based on morphometrical laws contrast opacification gradient directly implies microcirculation and peripheral resistance influence on blood flow distribution. However, further research is needed.

Název v anglickém jazyce

Flow determination in pulmonary arteries using transluminal gradient

Popis výsledku anglicky

Computed tomography pulmonary angiography (CTPA) is a strong tool for estimating pulmonary arteries morphology. Nevertheless, it cannot supply quantitative information about hemodynamics. Creating patient-specific models is a novel method of diagnosing, which allows to assess the flow and pressure behaviour in the stenosed vessels in patients with chronical thromboembolic pulmonary hypertension. 3D model of pulmonary arteries is extracted from the set of CTPA image data and the 3D point cloud is exported. Since each point is defined with 3 spatial coordinates and Hounsfield unit respectively it is possible to follow the change of contrast medium concentration along the pulmonary arteries up to the periphery. Absolute value of flow rate in artery directly from the CT scan is calculated using only several parameters, such as average cross-sectional area of the vessel, distance from the ostium and contrast bolus duration. Transluminal gradient method of flow rate determination is used to obtain outlet boundary conditions for further blood flow simulation. In comparison with boundary condition calculation based on morphometrical laws contrast opacification gradient directly implies microcirculation and peripheral resistance influence on blood flow distribution. However, further research is needed.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20601 - Medical engineering

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

INSTRUMENTS AND METHODS IN BIOLOGY AND MEDICINE 2022

ISBN

978-80-01-07065-9

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

23-27

Název nakladatele

České vysoké učení technické v Praze

Místo vydání

Praha

Místo konání akce

Kladno

Datum konání akce

19. 5. 2022

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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