Vessel density and retinal nerve fiber layer in pathological intraocular pressure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00383612" target="_blank" >RIV/68407700:21460/25:00383612 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.31348/2025/16" target="_blank" >https://doi.org/10.31348/2025/16</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.31348/2025/16" target="_blank" >10.31348/2025/16</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Vessel density and retinal nerve fiber layer in pathological intraocular pressure

Popis výsledku v původním jazyce

AIM: The aim of the study was to determine the correlation between intraocular pressure (IOP) and thickness of the retinal nerve fiber layer (RNFL), and vascular density (VD) in the optic nerve. MATERIAL AND METHODOLOGY: IOP was greater than 21 mmHg (21-36 mmHg) in all eyes and was measured as the result of an average of three measurements with the instrument Ocular Response Analyzer (ORA, Reichert). RNFL and VD thickness (in the papillary region of 4.5 x 4.5 mm) was measured with the instrument Avanti RTVue XR (Optovue). In the case of the VD, the scan area was further separated into individual anatomical segments. In the case of corrected RNFL (RNFLc), the VD value was subtracted from the total RNFL value. The relationship of IOP to VD, RNFL and RNFLc in each peripapillary segment was determined using a Pearson's correlation coefficient. RESULTS: The most significant correlation with IOP was observed for small vessel VD in a full scan (r = -0.48) and VD in the IT segment (r = -0.48). A similar correlation was observed for IOP and RNFL (r = -0.42). No statistically significant correlation was observed for RNFLc. CONCLUSION: We demonstrated that VD values, specifically WI-VDs and peripapillary VDs in the IT segment, are significant markers for the early diagnosis of glaucoma.

Název v anglickém jazyce

Vessel density and retinal nerve fiber layer in pathological intraocular pressure

Popis výsledku anglicky

AIM: The aim of the study was to determine the correlation between intraocular pressure (IOP) and thickness of the retinal nerve fiber layer (RNFL), and vascular density (VD) in the optic nerve. MATERIAL AND METHODOLOGY: IOP was greater than 21 mmHg (21-36 mmHg) in all eyes and was measured as the result of an average of three measurements with the instrument Ocular Response Analyzer (ORA, Reichert). RNFL and VD thickness (in the papillary region of 4.5 x 4.5 mm) was measured with the instrument Avanti RTVue XR (Optovue). In the case of the VD, the scan area was further separated into individual anatomical segments. In the case of corrected RNFL (RNFLc), the VD value was subtracted from the total RNFL value. The relationship of IOP to VD, RNFL and RNFLc in each peripapillary segment was determined using a Pearson's correlation coefficient. RESULTS: The most significant correlation with IOP was observed for small vessel VD in a full scan (r = -0.48) and VD in the IT segment (r = -0.48). A similar correlation was observed for IOP and RNFL (r = -0.42). No statistically significant correlation was observed for RNFLc. CONCLUSION: We demonstrated that VD values, specifically WI-VDs and peripapillary VDs in the IT segment, are significant markers for the early diagnosis of glaucoma.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ceska a Slovenska Oftalmologie

ISSN

1211-9059

e-ISSN

—

Svazek periodika

2025

Číslo periodika v rámci svazku

15

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

1-5

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-105001999302