C60 Fullerene Derivative: Radioprotectiva Properties and a Toxicity Test in Vivo and in Vitro

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70565813%3A_____%2F12%3A%230000289" target="_blank" >RIV/70565813:_____/12:#0000289 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

C60 Fullerene Derivative: Radioprotectiva Properties and a Toxicity Test in Vivo and in Vitro

Popis výsledku v původním jazyce

The scope of use fullerenes and their derivatives, thank to their material and bonding properties, is increasing, including their application in biological system. The possibility of their use as substances affecting to the effect of ioninising radiationwas examined experimentally in vivo individual of Danio rerio in jeveline age )2,5 months) without differentiated sex and in vitro in tissue cultures in primoculture of guinea pig kidney cells and in melanoma cells B16-F10, parallelto the toxicty test. in order to achieve the accessibility of fullerenes for living organisms the reaction of C60 fullerene with peracetigacid and followed by hydrolysis of oxo-fullerene prapared in water-soluble fullerene derivative characterised by its Fourrier transformation infra-red spectrum (FTIR), and in its solution at a concentration of 147mg/L individuals of the jevenile form of Danio rerio can survive for a long time without sings of toxic effect. A radioprotective effect was showen in fish after t

Název v anglickém jazyce

C60 Fullerene Derivative: Radioprotectiva Properties and a Toxicity Test in Vivo and in Vitro

Popis výsledku anglicky

The scope of use fullerenes and their derivatives, thank to their material and bonding properties, is increasing, including their application in biological system. The possibility of their use as substances affecting to the effect of ioninising radiationwas examined experimentally in vivo individual of Danio rerio in jeveline age )2,5 months) without differentiated sex and in vitro in tissue cultures in primoculture of guinea pig kidney cells and in melanoma cells B16-F10, parallelto the toxicty test. in order to achieve the accessibility of fullerenes for living organisms the reaction of C60 fullerene with peracetigacid and followed by hydrolysis of oxo-fullerene prapared in water-soluble fullerene derivative characterised by its Fourrier transformation infra-red spectrum (FTIR), and in its solution at a concentration of 147mg/L individuals of the jevenile form of Danio rerio can survive for a long time without sings of toxic effect. A radioprotective effect was showen in fish after t

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

—

Projekt

<a href="/cs/project/VG20102014049" target="_blank" >VG20102014049: Výzkum možností aplikace nových materiálů (se zaměřením na nanomateriály) a progresivních technologií k ochraně osob proti působení CBRN látek s důrazem na kritickou infrastrukturu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Materials Science and Engineerin A

ISSN

2161-6213

e-ISSN

—

Svazek periodika

2

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

302-312

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—