Influence of 1-monoacylglycerol of perfluoroundecanoic acid on growth inhibition of micromycetes

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of 1-monoacylglycerol of perfluoroundecanoic acid on growth inhibition of micromycetes

Popis výsledku v původním jazyce

The microbicidal and antifungal effects of monoacylglycerols have been extensively studied recently. Perfluorinated derivatives are also known to posses inhibitory activity against bacteria and micromycetes. In this study 1-monoacylglycerol of perfluoroundecanoic acid (MAG-C11:0(PF)) was prepared and tested for growth inhibition of selected species of micromycetes (Alternaria alternata, Aspergillus niger, Mucor racemosus and Penicillium roqueforti). The inhibition effect was evaluated by comparing the area of the colony on the culture medium containing MAG relative to that with no MAG added. Growth parameters, e.g. maximal radial growth rate, lag phase and minimum detection time were also monitored and compared. Results showed that M. racemosus was themost sensitive of all fungi species tested. MAG-C11:0(PF) showed a very strong inhibition effect against this species at a concentration of 750 ?g/ml. All other strains showed a strong or very strong inhibition effect at MAG-C11:0(PF) co

Název v anglickém jazyce

Influence of 1-monoacylglycerol of perfluoroundecanoic acid on growth inhibition of micromycetes

Popis výsledku anglicky

The microbicidal and antifungal effects of monoacylglycerols have been extensively studied recently. Perfluorinated derivatives are also known to posses inhibitory activity against bacteria and micromycetes. In this study 1-monoacylglycerol of perfluoroundecanoic acid (MAG-C11:0(PF)) was prepared and tested for growth inhibition of selected species of micromycetes (Alternaria alternata, Aspergillus niger, Mucor racemosus and Penicillium roqueforti). The inhibition effect was evaluated by comparing the area of the colony on the culture medium containing MAG relative to that with no MAG added. Growth parameters, e.g. maximal radial growth rate, lag phase and minimum detection time were also monitored and compared. Results showed that M. racemosus was themost sensitive of all fungi species tested. MAG-C11:0(PF) showed a very strong inhibition effect against this species at a concentration of 750 ?g/ml. All other strains showed a strong or very strong inhibition effect at MAG-C11:0(PF) co

Druh

O - Ostatní výsledky

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů