Effect of vehicle on the performance of active moisturizing substances

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F15%3A43873248" target="_blank" >RIV/70883521:28110/15:43873248 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1111/srt.12206" target="_blank" >http://dx.doi.org/10.1111/srt.12206</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/srt.12206" target="_blank" >10.1111/srt.12206</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of vehicle on the performance of active moisturizing substances

Popis výsledku v původním jazyce

Purpose: The work is aimed at the description and study of the hydration effect of different active substances (hyaluronic acid, sericin, glycerol, and urea) incorporated in two different vehicles commonly used for compounding pharmaceutical ingredients,gel, and emulsion. Methods: The effects of the formulations were investigated by instrumental methods in vivo after their administration to the skin of volar forearms in a group of 20 healthy volunteers (women, mean age of 28 years). Hydration effect was observed by corneometry and barrier properties (TEWL) by tewametr at regular time intervals (1-26 h) after application of the prepared samples. Results: The results indicate that the active substances incorporated in the emulsion moisturize the skin better compared to the same substances contained in the gel. Furthermore, it was found that these ingredients, whether they are present in the emulsion or in the gel, prevent TEWL in a similar manner. Conclusion: The study showed that diffe

Název v anglickém jazyce

Effect of vehicle on the performance of active moisturizing substances

Popis výsledku anglicky

Purpose: The work is aimed at the description and study of the hydration effect of different active substances (hyaluronic acid, sericin, glycerol, and urea) incorporated in two different vehicles commonly used for compounding pharmaceutical ingredients,gel, and emulsion. Methods: The effects of the formulations were investigated by instrumental methods in vivo after their administration to the skin of volar forearms in a group of 20 healthy volunteers (women, mean age of 28 years). Hydration effect was observed by corneometry and barrier properties (TEWL) by tewametr at regular time intervals (1-26 h) after application of the prepared samples. Results: The results indicate that the active substances incorporated in the emulsion moisturize the skin better compared to the same substances contained in the gel. Furthermore, it was found that these ingredients, whether they are present in the emulsion or in the gel, prevent TEWL in a similar manner. Conclusion: The study showed that diffe

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Skin Research and Technology

ISSN

0909-752X

e-ISSN

—

Svazek periodika

21

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

403-412

Kód UT WoS článku

000362679600003

EID výsledku v databázi Scopus

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