Influence of self-organized fluid flows on secondary and tertiary structure of bio-macromolecular system

Kód výsledku v IS VaVaI

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RIV/70883521:28610/17:63510508

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of self-organized fluid flows on secondary and tertiary structure of bio-macromolecular system

Popis výsledku v původním jazyce

Spatial arrangement of bio-macromolecular systems affects their function and role in physiological processes, as is generally known. The modification of the secondary and tertiary structure of the given system occurs due to the changes of temperature, pH, ionic strength, shear forces, etc. In this work is presented a new approach enabling initiation the changes of secondary and tertiary structure of the macromolecular system in the solution without modification the pH or ionic strength of the system. For this purpose is used the self-organized fluid flow in the form of Bénard-Marangoni convective instability. The result of continuously repeating the uneven shear strain of macromolecules in organized flowing solution is the change of mean coil size, its thermal stability and self-organizing capabilities, manifested through the changes in the surface activity at the interfaces or during the formation of self-supporting polymeric film. These changes can have significant implications, for example in producing smooth thin foils for medicinal application.

Název v anglickém jazyce

Influence of self-organized fluid flows on secondary and tertiary structure of bio-macromolecular system

Popis výsledku anglicky

Spatial arrangement of bio-macromolecular systems affects their function and role in physiological processes, as is generally known. The modification of the secondary and tertiary structure of the given system occurs due to the changes of temperature, pH, ionic strength, shear forces, etc. In this work is presented a new approach enabling initiation the changes of secondary and tertiary structure of the macromolecular system in the solution without modification the pH or ionic strength of the system. For this purpose is used the self-organized fluid flow in the form of Bénard-Marangoni convective instability. The result of continuously repeating the uneven shear strain of macromolecules in organized flowing solution is the change of mean coil size, its thermal stability and self-organizing capabilities, manifested through the changes in the surface activity at the interfaces or during the formation of self-supporting polymeric film. These changes can have significant implications, for example in producing smooth thin foils for medicinal application.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů