Antibacterial polyurethane / hydrophobic carbon quantum dots composites for biomedical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521368" target="_blank" >RIV/70883521:28110/18:63521368 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/18:63521368

Výsledek na webu

<a href="http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf" target="_blank" >http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Antibacterial polyurethane / hydrophobic carbon quantum dots composites for biomedical applications

Popis výsledku v původním jazyce

Hydrophobic carbon quantum dots (hCQDs) and newly prepared polyurethane nanocomposites with hCQDs work on the principle of photodynamic therapy. This material is able to produce reactive oxygen species, in this case singlet oxygen, after irradiation with light of appropriate wavelength. Polymer nanocomposites were prepared by simple swell-encapsulation-shrink method from a hydrophobic carbon quantum dots solution with the size of hCQDs of approximately 5 nm. Their antibacterial effect was tested on two bacteria, namely Escherichia coli and Staphylococcus aureus, which are widely spread, for example in hospital facilities. Cytotoxicity of prepared nanocomposites was tested on mouse embryonic fibroblast cell line and on adenocarcinomic human epithelial cell line. Electron paramagnetic resonance and near infrared fluorescence were used for determination of singlet oxygen production. The structure and other properties of the polymer composites were characterized by atomic force microscopy, transmission electron microscopy, X-photoelectron spectroscopy, photoluminescence spectroscopy, Raman spectroscopy, Fourier-transform infrared spectroscopy and others. The polyurethane / hCQDs composite is a financially and time-saving material and it has a wide range of applications. This material can be used as an antibacterial surface with high effectiveness, for example as flooring material, coatings, coated products, wall and window covering, catheters and other applications where antibacterial effect is required, particularly in medical, biomedical applications and in many other types of industrial production.

Název v anglickém jazyce

Antibacterial polyurethane / hydrophobic carbon quantum dots composites for biomedical applications

Popis výsledku anglicky

Hydrophobic carbon quantum dots (hCQDs) and newly prepared polyurethane nanocomposites with hCQDs work on the principle of photodynamic therapy. This material is able to produce reactive oxygen species, in this case singlet oxygen, after irradiation with light of appropriate wavelength. Polymer nanocomposites were prepared by simple swell-encapsulation-shrink method from a hydrophobic carbon quantum dots solution with the size of hCQDs of approximately 5 nm. Their antibacterial effect was tested on two bacteria, namely Escherichia coli and Staphylococcus aureus, which are widely spread, for example in hospital facilities. Cytotoxicity of prepared nanocomposites was tested on mouse embryonic fibroblast cell line and on adenocarcinomic human epithelial cell line. Electron paramagnetic resonance and near infrared fluorescence were used for determination of singlet oxygen production. The structure and other properties of the polymer composites were characterized by atomic force microscopy, transmission electron microscopy, X-photoelectron spectroscopy, photoluminescence spectroscopy, Raman spectroscopy, Fourier-transform infrared spectroscopy and others. The polyurethane / hCQDs composite is a financially and time-saving material and it has a wide range of applications. This material can be used as an antibacterial surface with high effectiveness, for example as flooring material, coatings, coated products, wall and window covering, catheters and other applications where antibacterial effect is required, particularly in medical, biomedical applications and in many other types of industrial production.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/8X17021" target="_blank" >8X17021: Antibakteriální polymerní nanokompozity z uhlíkových nanočástic</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů