Antibacterial photodynamic activity of hydrophobic carbon quantum dots and polycaprolactone based nanocomposite processed via both electrospinning and solvent casting method

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F21%3A63543938" target="_blank" >RIV/70883521:28110/21:63543938 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/21:63543938

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1572100021002799?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1572100021002799?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pdpdt.2021.102455" target="_blank" >10.1016/j.pdpdt.2021.102455</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antibacterial photodynamic activity of hydrophobic carbon quantum dots and polycaprolactone based nanocomposite processed via both electrospinning and solvent casting method

Popis výsledku v původním jazyce

Inhabitation of various types of bacteria on different surfaces causes vital health problems worldwide. In this work, a wound dressing defeating bacterial infection had been fabricated. The antibacterial effect of polycaprolactone and hydrophobic carbon quantum dots (hCQDs) based nanocomposite has been presented. The nanocomposite was fabricated both via solvent casting and electrospinning method. Nanocomposites with and without hCQDs had been investigated. A detailed study on their morphology and surface properties were performed by scanning electron microscopy, atomic force microscopy and Raman spectroscopy. Prepared nanocomposites had been evaluated by the contact angle, UV-Vis spectroscopy, electron paramagnetic resonance spectroscopy, and antibacterial activity. It was found that nanocomposites were able to produce singlet oxygen upon blue light irradiation at 470 nm, and they were effective in the eradication of Gram positive (Staphylococcus aureus, Listeria monocytogenes) and Gram negative (Escherichia coli, Klebsiella pneumoniae) bacteria.

Název v anglickém jazyce

Antibacterial photodynamic activity of hydrophobic carbon quantum dots and polycaprolactone based nanocomposite processed via both electrospinning and solvent casting method

Popis výsledku anglicky

Inhabitation of various types of bacteria on different surfaces causes vital health problems worldwide. In this work, a wound dressing defeating bacterial infection had been fabricated. The antibacterial effect of polycaprolactone and hydrophobic carbon quantum dots (hCQDs) based nanocomposite has been presented. The nanocomposite was fabricated both via solvent casting and electrospinning method. Nanocomposites with and without hCQDs had been investigated. A detailed study on their morphology and surface properties were performed by scanning electron microscopy, atomic force microscopy and Raman spectroscopy. Prepared nanocomposites had been evaluated by the contact angle, UV-Vis spectroscopy, electron paramagnetic resonance spectroscopy, and antibacterial activity. It was found that nanocomposites were able to produce singlet oxygen upon blue light irradiation at 470 nm, and they were effective in the eradication of Gram positive (Staphylococcus aureus, Listeria monocytogenes) and Gram negative (Escherichia coli, Klebsiella pneumoniae) bacteria.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GA20-28732S" target="_blank" >GA20-28732S: Koloidní systémy pro topické formulace. Pickeringovy emulze a koloidy na bázi polymerů.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Photodiagnosis and Photodynamic Therapy

ISSN

1572-1000

e-ISSN

—

Svazek periodika

35

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

—

Kód UT WoS článku

000696990900005

EID výsledku v databázi Scopus

2-s2.0-85111544701