On the development and characterisation of crosslinked sodium alginate/gelatine hydrogels

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F13%3A43869741" target="_blank" >RIV/70883521:28610/13:43869741 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S1751616112003220" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1751616112003220</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jmbbm.2012.11.010" target="_blank" >10.1016/j.jmbbm.2012.11.010</a>

Jazyk výsledku

angličtina

Název v původním jazyce

On the development and characterisation of crosslinked sodium alginate/gelatine hydrogels

Popis výsledku v původním jazyce

Sodium alginate (SA) and gelatine (G) based hydrogels with various SA/G ratios, crosslinked with calcium ions (Ca2+) and glutaraldehyde (GTA), respectively, were developed. Scanning electron microscopy, Fourier transform infrared spectroscopy (FTIR), anddynamic mechanical analysis (DMA) were applied to determine their physicochemical characterization. The swelling studies, conducted in phosphate-buffered saline with a pH ranging from 1 to 11 at 37°C, were utilized for an evaluation of their absorptionability. FTIR spectra of the Ca2+ crosslinked SA/G hydrogels revealed a small shift in symmetric stretching carboxyl groups, indicating an ionic binding between the Ca2+ ions and the SA. Increasing the G content in hydrogels crosslinked with GTA significantly changed the shapes of the amide I and II bands in the FTIR spectra, thus confirming the G-GTA crosslink formation. After crosslinking, a DMA study proved the enhanced viscoelastic properties and improved thermal stability of the pre

Název v anglickém jazyce

On the development and characterisation of crosslinked sodium alginate/gelatine hydrogels

Popis výsledku anglicky

Sodium alginate (SA) and gelatine (G) based hydrogels with various SA/G ratios, crosslinked with calcium ions (Ca2+) and glutaraldehyde (GTA), respectively, were developed. Scanning electron microscopy, Fourier transform infrared spectroscopy (FTIR), anddynamic mechanical analysis (DMA) were applied to determine their physicochemical characterization. The swelling studies, conducted in phosphate-buffered saline with a pH ranging from 1 to 11 at 37°C, were utilized for an evaluation of their absorptionability. FTIR spectra of the Ca2+ crosslinked SA/G hydrogels revealed a small shift in symmetric stretching carboxyl groups, indicating an ionic binding between the Ca2+ ions and the SA. Increasing the G content in hydrogels crosslinked with GTA significantly changed the shapes of the amide I and II bands in the FTIR spectra, thus confirming the G-GTA crosslink formation. After crosslinking, a DMA study proved the enhanced viscoelastic properties and improved thermal stability of the pre

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F03.0111" target="_blank" >ED2.1.00/03.0111: Centrum polymerních systémů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the Mechanical Behavior of Biomedical Materials

ISSN

1751-6161

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

15

Strana od-do

152-166

Kód UT WoS článku

000316585400016

EID výsledku v databázi Scopus

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