Formulation and characterization of 1-monoacylglycerols-loaded microemulsions

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Formulation and characterization of 1-monoacylglycerols-loaded microemulsions

Popis výsledku v původním jazyce

Microemulsions have recently attracted attention as useful carriers of active substances, which offer opportunities for the encapsulation of both water-soluble and oil-soluble compounds. Due to their beneficial physico-chemical properties, they are applicable in the cosmetic, pharmaceutical and food industry. The objective of the study was to investigate the effect of various co-surfactants on the formulations of o/w microemulsions containing 1-monoacylglycerols (1-MAG) with fatty acids of different chain length, namely capric (C10:0), lauric (C12:0) and myristic (C14:0) acids. Medium-chain length alcohols (ethanol, 1-propanol, 1-butanol, 1-pentanol) were used as co-surfactants, and Tween 80 as a surfactant. Phase behaviour of the emulsion systems wasstudied with the help of pseudo-ternary phase diagrams, which were then used to determine final composition of microemulsions. On the optimum formulations, the size of the microemulsion droplets was determined using photon correlation spe

Název v anglickém jazyce

Formulation and characterization of 1-monoacylglycerols-loaded microemulsions

Popis výsledku anglicky

Microemulsions have recently attracted attention as useful carriers of active substances, which offer opportunities for the encapsulation of both water-soluble and oil-soluble compounds. Due to their beneficial physico-chemical properties, they are applicable in the cosmetic, pharmaceutical and food industry. The objective of the study was to investigate the effect of various co-surfactants on the formulations of o/w microemulsions containing 1-monoacylglycerols (1-MAG) with fatty acids of different chain length, namely capric (C10:0), lauric (C12:0) and myristic (C14:0) acids. Medium-chain length alcohols (ethanol, 1-propanol, 1-butanol, 1-pentanol) were used as co-surfactants, and Tween 80 as a surfactant. Phase behaviour of the emulsion systems wasstudied with the help of pseudo-ternary phase diagrams, which were then used to determine final composition of microemulsions. On the optimum formulations, the size of the microemulsion droplets was determined using photon correlation spe

Druh

O - Ostatní výsledky

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů