Biomineralized hydroxyapatite/graphene oxide/bacterial cellulose scaffold for bone tissue engineering: A green synthesis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F23%3A63574759" target="_blank" >RIV/70883521:28610/23:63574759 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biomineralized hydroxyapatite/graphene oxide/bacterial cellulose scaffold for bone tissue engineering: A green synthesis

Popis výsledku v původním jazyce

Biomineralization is a process where biominerals such as carbonates, silicates and phosphates are formed through biological actions of micro-organisms. Its main applications include bone tissue engineering. In this study, hydroxyapatite (HA) will be biomineralized from natural sources, i.e. agricultural biomass. The produced HA will be used to provide the calcium phosphate mineral necessary for bone regeneration. To enhance its properties, it will be used as a biocomposite scaffold with graphene oxide, for a better mechanical property, and bacterial cellulose, to compliment the biocompatibility and cell growth. The graphene oxide will also be produced from agricultural residue, whereas the bacterial cellulose is derived from fruit waste media. The production process proves to be environmentally sustainable. The scaffold will be tested for morphology, hydrophilicity, mechanical strength and biocompatibility. The researchers expect that the results will show a biocompatible and mechanically stable scaffold made in a sustainable process.

Název v anglickém jazyce

Biomineralized hydroxyapatite/graphene oxide/bacterial cellulose scaffold for bone tissue engineering: A green synthesis

Popis výsledku anglicky

Biomineralization is a process where biominerals such as carbonates, silicates and phosphates are formed through biological actions of micro-organisms. Its main applications include bone tissue engineering. In this study, hydroxyapatite (HA) will be biomineralized from natural sources, i.e. agricultural biomass. The produced HA will be used to provide the calcium phosphate mineral necessary for bone regeneration. To enhance its properties, it will be used as a biocomposite scaffold with graphene oxide, for a better mechanical property, and bacterial cellulose, to compliment the biocompatibility and cell growth. The graphene oxide will also be produced from agricultural residue, whereas the bacterial cellulose is derived from fruit waste media. The production process proves to be environmentally sustainable. The scaffold will be tested for morphology, hydrophilicity, mechanical strength and biocompatibility. The researchers expect that the results will show a biocompatible and mechanically stable scaffold made in a sustainable process.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů