The effect of synthesis method and oxidizing agent on cytotoxicity and ecotoxicity of polyaniline

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F24%3A63574238" target="_blank" >RIV/70883521:28610/24:63574238 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28110/24:63574238

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0379677923002370?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0379677923002370?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.synthmet.2023.117515" target="_blank" >10.1016/j.synthmet.2023.117515</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The effect of synthesis method and oxidizing agent on cytotoxicity and ecotoxicity of polyaniline

Popis výsledku v původním jazyce

The unique properties of polyaniline (PANI), as representative of conducting polymers (CPs) predetermine their use in biomedical field. While the material properties of PANI prepared by chemical or microwave synthesis are well known, their biological properties have not been adequately addressed and compared. To fill this gap, PANI powders were prepared by either chemical or microwave synthesis using different oxidizing agent (ammonium persulfate, APS vs potassium iodate, KIO3) and studied. The effect on cytotoxicity and ecotoxicity were determined according to the ISO protocol and inhibition of bioluminescence in Photobacterium phosphoreum, respectively. The significant effect of both factors, the synthesis route and oxidizing agent, on biological performance was confirmed. The choice of optimum preparation condition for PANI synthesis highly improved its cytotoxicity and ecotoxicity compared to previously described PANI forms. Results of the here presented work are crucial for the further utilization of PANI in wide spectrum of biomedical applications.

Název v anglickém jazyce

The effect of synthesis method and oxidizing agent on cytotoxicity and ecotoxicity of polyaniline

Popis výsledku anglicky

The unique properties of polyaniline (PANI), as representative of conducting polymers (CPs) predetermine their use in biomedical field. While the material properties of PANI prepared by chemical or microwave synthesis are well known, their biological properties have not been adequately addressed and compared. To fill this gap, PANI powders were prepared by either chemical or microwave synthesis using different oxidizing agent (ammonium persulfate, APS vs potassium iodate, KIO3) and studied. The effect on cytotoxicity and ecotoxicity were determined according to the ISO protocol and inhibition of bioluminescence in Photobacterium phosphoreum, respectively. The significant effect of both factors, the synthesis route and oxidizing agent, on biological performance was confirmed. The choice of optimum preparation condition for PANI synthesis highly improved its cytotoxicity and ecotoxicity compared to previously described PANI forms. Results of the here presented work are crucial for the further utilization of PANI in wide spectrum of biomedical applications.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30404 - Biomaterials (as related to medical implants, devices, sensors)

Projekt

<a href="/cs/project/GA23-07425S" target="_blank" >GA23-07425S: Anisotropní a elektricky vodivé biomateriály</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Synthetic Metals

ISSN

0379-6779

e-ISSN

—

Svazek periodika

301

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

10

Strana od-do

—

Kód UT WoS článku

001125064400001

EID výsledku v databázi Scopus

2-s2.0-85178027362