Investigation of ochratoxin A and citrinin occurrence in medicinal herbal products from the Czech market

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F25%3A00015134" target="_blank" >RIV/75010330:_____/25:00015134 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62690094:18470/25:50022420

Výsledek na webu

<a href="https://link.springer.com/content/pdf/10.1007/s40264-025-01570-5.pdf?utm_source=clarivate&getft_integrator=clarivate" target="_blank" >https://link.springer.com/content/pdf/10.1007/s40264-025-01570-5.pdf?utm_source=clarivate&getft_integrator=clarivate</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s40264-025-01570-5" target="_blank" >10.1007/s40264-025-01570-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Investigation of ochratoxin A and citrinin occurrence in medicinal herbal products from the Czech market

Popis výsledku v původním jazyce

IntroductionMedicinal plants are extensively utilized as dietary supplements to encourage disease prevention and to support the treatment of various health disorders. Unfortunately, several plants are known for mycotoxin contamination, which may overwhelm any beneficial effects the plants might have.ObjectiveThe purpose of the study was to determine the presence of ochratoxin A (OTA) and citrinin (CIT) in medicinal herbal products (MHP).MethodsSixty samples of different MHP types were purchased on the Czech market during 2020-2021. Both mycotoxins were determined using high-performance liquid chromatography with a fluorescence detector with immunoaffinity columns employed as a pretreatment.ResultsIn total, 40% and 27% of samples were above the limit of quantification with the concentrations ranging up to 826.62 ng/g and 472.79 ng/g for OTA and CIT, respectively. The co-occurrence was confirmed in six MHP types.ConclusionsMHP could be a significant source of OTA and CIT. To protect the health of MHP users, it is desirable to continue monitoring the presence of mycotoxins in MHP. During this study, new OTA regulations for herbs came into force in the EU.

Název v anglickém jazyce

Investigation of ochratoxin A and citrinin occurrence in medicinal herbal products from the Czech market

Popis výsledku anglicky

IntroductionMedicinal plants are extensively utilized as dietary supplements to encourage disease prevention and to support the treatment of various health disorders. Unfortunately, several plants are known for mycotoxin contamination, which may overwhelm any beneficial effects the plants might have.ObjectiveThe purpose of the study was to determine the presence of ochratoxin A (OTA) and citrinin (CIT) in medicinal herbal products (MHP).MethodsSixty samples of different MHP types were purchased on the Czech market during 2020-2021. Both mycotoxins were determined using high-performance liquid chromatography with a fluorescence detector with immunoaffinity columns employed as a pretreatment.ResultsIn total, 40% and 27% of samples were above the limit of quantification with the concentrations ranging up to 826.62 ng/g and 472.79 ng/g for OTA and CIT, respectively. The co-occurrence was confirmed in six MHP types.ConclusionsMHP could be a significant source of OTA and CIT. To protect the health of MHP users, it is desirable to continue monitoring the presence of mycotoxins in MHP. During this study, new OTA regulations for herbs came into force in the EU.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Drug Safety

ISSN

0114-5916

e-ISSN

1179-1942

Svazek periodika

48

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

13

Strana od-do

1215-1227

Kód UT WoS článku

001506913300001

EID výsledku v databázi Scopus

2-s2.0-105007881796