Lung cancer mortality among Czech uranium miners - 60 years since exposure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652052%3A_____%2F12%3A%230000060" target="_blank" >RIV/86652052:_____/12:#0000060 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1088/0952-4746/32/3/301" target="_blank" >http://dx.doi.org/10.1088/0952-4746/32/3/301</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/0952-4746/32/3/301" target="_blank" >10.1088/0952-4746/32/3/301</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lung cancer mortality among Czech uranium miners - 60 years since exposure

Popis výsledku v původním jazyce

The study is based on 9978 Czech uranium miners with 1141 lung cancers observed in updated follow-up 1952-2010. Lung cancer risk in relation to cumulated exposure to radon decay products is linear with substantial modifications by time since exposure, age at exposure, and exposure rate. The crude excess relative risk (ERR) per unit exposure in working level months (WLM) in the cohort is 0.0097 (90%CI: 0.0074-0.0127). The ERR/WLM corresponding to exposure rates below 7 working levels (WL) is substantially higher - 0.0145 (90%CI: 0.0109?0.0193). In the final model, the inverse effect of exposure rate is observed for high exposure rates > 7WL with the ERR/WLM reduced to 31% . The ERR/WLM decreases to 32% and 9% in periods 20-29 and 30+ years since exposure in comparison to period 5-19 years since exposure. Simultaneously, the ERR/WLM decreases with age at exposure ? 63% and 49% at ages 30-39 and 40+ years in comparison to age at exposure <30 years.

Název v anglickém jazyce

Lung cancer mortality among Czech uranium miners - 60 years since exposure

Popis výsledku anglicky

The study is based on 9978 Czech uranium miners with 1141 lung cancers observed in updated follow-up 1952-2010. Lung cancer risk in relation to cumulated exposure to radon decay products is linear with substantial modifications by time since exposure, age at exposure, and exposure rate. The crude excess relative risk (ERR) per unit exposure in working level months (WLM) in the cohort is 0.0097 (90%CI: 0.0074-0.0127). The ERR/WLM corresponding to exposure rates below 7 working levels (WL) is substantially higher - 0.0145 (90%CI: 0.0109?0.0193). In the final model, the inverse effect of exposure rate is observed for high exposure rates > 7WL with the ERR/WLM reduced to 31% . The ERR/WLM decreases to 32% and 9% in periods 20-29 and 30+ years since exposure in comparison to period 5-19 years since exposure. Simultaneously, the ERR/WLM decreases with age at exposure ? 63% and 49% at ages 30-39 and 40+ years in comparison to age at exposure <30 years.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

<a href="/cs/project/NS10596" target="_blank" >NS10596: Zdravotní rizika vyplývající z expozice radonu v pracovním a životním prostředí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Radiological Protection

ISSN

0952-4746

e-ISSN

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Svazek periodika

32

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

301-314

Kód UT WoS článku

000308348500011

EID výsledku v databázi Scopus

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