Effect of age at exposure in 11 underground miners studies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652052%3A_____%2F14%3A%230000268" target="_blank" >RIV/86652052:_____/14:#0000268 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1093/rpd/ncu068" target="_blank" >http://dx.doi.org/10.1093/rpd/ncu068</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/rpd/ncu068" target="_blank" >10.1093/rpd/ncu068</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of age at exposure in 11 underground miners studies

Popis výsledku v původním jazyce

Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time.

Název v anglickém jazyce

Effect of age at exposure in 11 underground miners studies

Popis výsledku anglicky

Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Radiation Protection Dosimetry

ISSN

0144-8420

e-ISSN

—

Svazek periodika

160

Číslo periodika v rámci svazku

1-3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

124-127

Kód UT WoS článku

000339953000031

EID výsledku v databázi Scopus

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