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19 612 (0,107s)

Výsledek výzkumu

Influence of metabolic state and body composition on the action of pharmacological treatment of migraine

of antimigraine drugs could be altered in patients with both migraine and metabolic disease of antimigraine drugs in patients with metabolic disease are limited. Therefore, and given composition on the action of <...

Clinical medicine

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells

The efforts for therapeutic targeting of the aryl hydrocarbon receptor (AhR) have emerged in recent years. We investigated the effects of available antimigraine triptan drugs, having an indole core in their structure, on AhR signali...

Biochemistry and molecular biology

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Application of antiCGRP prophylaxis episodic and chronic migraines in praxis

Migraine is the third most common neurological disease. It i also one of the most disabling disease in the world. They are around one million patients with migraine in the Czech Republic. At least 50 000 women and men suffer from chronic migraine. Si...

Clinical neurology

  • 2022
  • Jost
  • Odkaz
Výsledek výzkumu

Biologic treatment of migraine

1993, we have had a specific acute antimigraine drug, triptans. Since 2020...

Clinical neurology

  • 2023
  • Jost
  • Odkaz
Výsledek výzkumu

Updated insight into the pathophysiology of migraine - an update

of a knowledge of pathophysiology on the development of specific antimigraine drugs...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011
  • Jx
Výsledek výzkumu

Natural products and their (semi-)synthetic forms in treatment of migraine: History and current status

targets for antimigraine drugs such as cannabinoid, histamine, and melatonin receptors of drugs have been used for treatment of migraine, most of these are not effective......

Medicinal chemistry

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Migraine - diagnostics and treatment

Mankind has suffered from headaches from time immemorial. Old Egyptians mentioned them in old papers in the year 1550 B.C. Therapeutic use of ergotamine and dihydroergotamine and especially the invention of various classes and subclasses of 5-HT rece...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003
  • B
Výsledek výzkumu

Hemiplegic migraine

Hemiplegic migraine is a very rare disease with a prevalence of 0.01%. This is the first type of migraine with a proven gene defect in chromosomes 19.1 and 19.2. The clinical picture typically includes motor impairment up to plegia (days to weeks). T...

Neurosciences (including psychophysiology)

  • 2017
  • Jost
Výsledek výzkumu

Butterbur in the treatment of migraine

have shown antimigraine action in clinical studies. Migraine research has...

Psychiatry

  • 2017
  • JSC
Výsledek výzkumu

Market price of illegal drugs as a war on drugs success indicator

Basic themes of document: drug supply; drug demand; drug price; War on Drugs; anti-drug measures; drug price elasticity of demand......

AD - Politologie a politické vědy

  • 2016
  • Jx
  • Odkaz
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