Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”

Filtry

11 392 (0,085s)

Výsledek výzkumu

Proteases and antiproteases in health and disease - a review III. Cysteine proteases and their natural inhibitors

Aberrations in cysteine protease and cysteine protease inhibitor expression is associated with a variety of pathological states....

CE - Biochemie

  • 2002
  • Jx
Výsledek výzkumu

Proteases and antiproteases in health and disease - a review III. Cysteine proteases and natural inhibitors

Current data indicate that lysosomal cysteine proteases and cytosolic caspases may play opposite roles in tumor growth and progression. A variety of neurodegenerative diseases are thought to be associated with unphysiological action...

FC - Pneumologie

  • 2002
  • Jx
Výsledek výzkumu

Serine proteinase inhibitors (serpins) inhibiting cysteine proteinases: an example of "cross-class" inhibition

The communication summarizes serine proteinase-type inhibitors, evolutionary converted to inhibitors of a mechanistically different cysteine protease class. This phenomenon is explained by a similar mechanism of a ...

Biochemistry and molecular biology

  • 2018
  • Jost
Výsledek výzkumu

Salivary protease inhibitors with non anti-hemostatic function

Herein we review the available literature with the aim to reveal that arthropod saliva is a rich source of protease inhibitors that through their action modulate non hemostatic mechanisms of the vertebrate host physiology....

EC - Imunologie

  • 2010
  • C
Výsledek výzkumu

Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases.

Aza-peptide Michael acceptors are irreversible inhibitors of clan CD cysteine proteases. Aza-peptide Michael acceptors showed no cross reactivity toward papain, cathepsin B, and calpain....

CE - Biochemie

  • 2004
  • Jx
Výsledek výzkumu

The use of monolitic columns for the separation of potato protease inhibitors using the fast protein liquid chromatography system

inhibitor I were major components in acidic fraction. The alkaline protease inhibitors were identified as isoforms of cysteine protease inhibitors, aspartate protease inhibitors...

Analytical chemistry

  • 2017
  • Jimp
Výsledek výzkumu

Tick cysteine protease inhibitors suppress immune responses in mannan-induced psoriasis-like inflammation

and scalp of the body, and the contribution of cysteine and serine proteases to the development of skin inflammation is well documented. Cysteine protease inhibitors fromProtease inhibitors

Microbiology

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Plant Kunitz protease inhibitors: Structural and functional diversity

proteases. The majority of characterized members of the Kunitz family are inhibitors of proteases of the serine class (S1 and S8 families); inhibitors of aspartic proteases (A1 family) and cysteine

CE - Biochemie

  • 2016
  • Jx
  • Odkaz
Výsledek výzkumu

Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity

Azapeptide nitriles are postulated to reversibly covalently react with the active-site cysteine residue of cysteine proteases and form isothiosemicarbazide adducts. We investigated the interaction of azadipeptide nitriles w...

Biochemistry and molecular biology

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Crystallization and diffraction analysis of the serpin IRS-2 from the hard tick Ixodes ricinus

of protease inhibitors. It is produced in the tick salivary glands, and its anti crystals. Activity profiling with specific substrates and inhibitors demonstrated traces of serine and cysteine proteases i...

CE - Biochemie

  • 2010
  • Jx
  • 1 - 10 z 11 392