Filtry
Poly(ADP-ribose) polymerase inhibitors in the treatment of myelodysplastic syndrome and acute myeloid leukemia
Chapter Four explains the utility of poly(ADP-ribose) polymerase inhibitors in the treatment of myelodysplastic syndrome and acute myeloid leukemia....
Hematology
- 2021 •
- C •
- Odkaz
Rok uplatnění
C - Kapitola v odborné knize
Výsledek na webu
Tumour Necrosis Factor alpha (TNFalpha) Induces Cell Death Associated with Cleavage of Poly (ADP-Ribose) Polymerase (PARP) in HT-29 Human Colon Adenosarcinoma Cell Line.
Cell death, associated with cleavage of poly(ADP-Ribose) polymerase(PARP)in HT-29 human colon adenosarcinoma cell line, is induced by tumour necrosis factor alpha......
BO - Biofyzika
- 2001 •
- D
Rok uplatnění
D - Stať ve sborníku
Bcl-2 prevents nitric oxide-mediated apoptosis and poly (ADP-ribose) polymerase clevage.
FP - Ostatní lékařské obory
- 1998 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication
Poly(ADP-ribose) is synthesized by PARP enzymes during the repair of stochastic DNA breaks. Surprisingly, however, we show that most if not all endogenous poly(ADP-ribose) is detected in normal S ...
Biochemistry and molecular biology
- 2018 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Oxidative stress
Analysis of the poly-(ADP-ribose) polymerase and 8-oxoguanin DNA glycosylase polymorphisms does not suggest its association with progression of diabetes....
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2008 •
- O
Rok uplatnění
O - Ostatní výsledky
Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis
Asbestos is known to induce malignant mesothelioma (MM). It is directly genotoxic by inducing DNA strand breaks. Poly(ADP-ribose) polymerase-1 (PARP1) is a protein with a function as a DNA damage sensor. To determi...
EB - Genetika a molekulární biologie
- 2011 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Thrombomodulin Is Silenced in Malignant Mesothelioma by a Poly(ADP-ribose) Polymerase-1-mediated Epigenetic Mechanism
We analyzed thrombomodulin (TM) expression in biopsies of malignant mesothelioma (MM) patients and compared with normal mesothelial tissue. To evaluate poly(ADP-ribose) polymerase-1 (PARP1) as responsible for gene ...
EB - Genetika a molekulární biologie
- 2011 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Perspectives on PARPs in S Phase
in anticancer therapy, are the poly (ADP-ribose) polymerases (PARPs). We review here...
Cell biology
- 2019 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity
via DNA-PK and poly(ADP-ribose) polymerase-1 (PARP-1) inhibition, while alone...
Biochemistry and molecular biology
- 2019 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
Poly(ADP-ribosyl)ation is a reversible post-translational modification synthetized by ADP-ribose transferases and removed by poly(ADP-ribose) glycohydrolase activity in poly(...
Cell biology
- 2020 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
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