Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”

Filtry

39 491 (0,165s)

Výsledek výzkumu

Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines

Dihydroxylation of 6-vinylpurines gave 6-(1,2-dihydroxyethyl)purines, while the epoxidation afforded 6-(oxiran-2-yl)purines which underwent ring-opening reactions with diverse nucleophiles to give a series of title...

CC - Organická chemie

  • 2008
  • Jx
Výsledek výzkumu

Synthesis and properties of chiral open-ring acyclic nucleoside bisphosphonates

-diaminopurine with an open imidazole ring in the purine moiety.

CC - Organická chemie

  • 2005
  • D
Výsledek výzkumu

The study of cyclocondensation reaction of isocyclic and heterocyclic aminoderivatives and their using to synthesis of heterocycles with quinoxaline, triazine, pyrazole, purine and deaza- purine

The cyclocondensation reaction of isocyclic and heterocyclic aminoderivatives can be used to heterocycles with quinoxaline, triazine, pyrazole, purine and deaza- purine rings....

CC - Organická chemie

  • 2005
  • Jx
Výsledek výzkumu

Synthesis and properties of novel types of chiral open-ring acyclic nucleoside phosphonates

-diaminopurine with an open imidazole ring in the purine moiety.

CC - Organická chemie

  • 2005
  • Jx
Výsledek výzkumu

The Acyclic 2,4-Diaminopyrimidine Nucleoside Phosphonate Acts as a Purine Mimetic in HIV-1 Reverse Transcriptase DNA Polymerization

HIV-1 RT recognizes diphosphate of the acyclic pyrimidine nucleoside phosphonate (ANP) phosphonylmethoxyethoxydiaminopyrimidine (PMEO-DAPym) as purine nucleotide analogue. Molecular modeling demonstrates that PMEO-DAPym-pp fits for the desig...

CC - Organická chemie

  • 2010
  • Jx
Výsledek výzkumu

Purine de novo synthesis - mechanisms and clinical implications

Purine de novo synthesis represents a basis for nucleotide metabolism as well as all other interconnected pathways. Synthesis of the purine ring de novo is required especially when DNA is replicated so that, although presen...

CE - Biochemie

  • 2005
  • Jx
Výsledek výzkumu

(1-Adamantyl){4-[(2-chloro-9-isopropyl-9H-purin-6-yl)aminomethyl]phenyl}methanone trichloromethane solvate

In the title compound, C26H30ClN5O?CHCl3, the purine molecule consists of essentially planar benzene and purine ring systems [maximum deviation 0.010 (4) ? for both ring systems] forming a dihedral angle of 85.52 (...

CC - Organická chemie

  • 2009
  • Jx
Výsledek výzkumu

N-Alkylpurine derivatives as model systems of purine tautomers: Study of substitution effects on solution-state NMR parameters

by electron distribution throughout the purine ring, which is governed by the natureand position of substituents on the purine ring. NMR chemical shifts and indirect spin-spinPurine derivatives as biologi...

CC - Organická chemie

  • 2006
  • O
Výsledek výzkumu

Synthesis and mass spectrometric fragmentation characteristics of imidazole ribosides-analogs of intermediates of purine de novo synthetic pathway

by the ion trap mass spectrometry. During fragmentation an opening of the imidazole ringTwo inherited deficiencies have been described in purine de novo synthesis pathway. Both the defects are diagnosed by detecting ribosi...

CE - Biochemie

  • 2006
  • Jx
Výsledek výzkumu

N-(2-Methoxybenzyl)-9-(oxolan-2-yl)-9H-purin-6-amine.

The title compound, C17H19N5O2, features an almost planar purine skeleton (r.m.s. deviation = 0.009 A) substituted by a tetrahydrofuran ring, which adopts an envelope conformation. The purine and benzene rings subt...

CC - Organická chemie

  • 2013
  • Jx
  • Odkaz
  • 1 - 10 z 39 491