Filtry
Towards functional repertoire of the earliest proteins
The conserved protein sequence motifs present in all prokaryotic proteomes, omnipresent motifs, presumably, correspond to the earliest proteins of the Last Universal Cellular Ancestor, from which all the proteomes ...
EB - Genetika a molekulární biologie
- 2013 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Web server to identify similarity of amino acid motifs to compounds (SAAMCO)
Protein-protein interactions are fundamental in mediating biological processes or induce protein activity or complex formation is a key feature in controlling disease. For those situations in which protein-prot...
CF - Fyzikální chemie a teoretická chemie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets
Motivation: Proteins often recognize their interaction partners on the basis of short linear motifs located in disordered regions on proteins' surface. Experimental techniques that study such motifs use short pepti...
EB - Genetika a molekulární biologie
- 2016 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors
ligand motif) motif in the Arginine-Rich Motif (ARM) of the Rev protein. ULMs (UHM ligand motif) mediate protein interactions during spliceosome assembly by binding to UHM (U2AF homology moti...
Biochemistry and molecular biology
- 2019 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Plant and yeast cornichon possess a conserved acidic motif required for correct targeting of plasma membrane cargos
The export of membrane proteins along the secretory pathway is initiated at the endoplasmic reticulum after proteins are folded and packaged inside this organelle are required for the correct transport of proteins to its ta...
Biochemistry and molecular biology
- 2017 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein).
Transmembrane adaptor protein SIT interacts with SHP2 butalso with Grb2 via two consensus YxN motifs. However, mutation of both Grb2-binding sites does not influence the inhibitory function of SIT. In contrast, mutation of the tyros...
EB - Genetika a molekulární biologie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Searching for G-Quadruplex-Binding Proteins in Plants: New Insight into Possible G-Quadruplex Regulation
), and revealed many proteins containing the G4-binding motif(s). Our research also revealed, neurological disorders). Several of the proteins for binding G-quadruplexes are known. Nonetheless, in plants, only a small numbe...
Environmental biotechnology
- 2021 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Tetratricopeptide Repeat Motifs in the World of Bacterial Pathogens: Role in Virulence Mechanisms
The tetratricopeptide repeat (TPR) structural motif is known to occur in a wide variety of proteins present in prokaryotic and eukaryotic organisms. The TPR motif,TPR-containing proteins often play roles in vital c...
EC - Imunologie
- 2013 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
SiteBinder: An improved approach for comparing multiple protein structural motifs
superimposition of large sets of protein structural motifs. Our superimposition methodology up to thousands of protein structural motifs in a very short time, and whichThere is a paramount need to develop new tech...
CF - Fyzikální chemie a teoretická chemie
- 2012 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
G-quadruplexes as regulatory motifs in p53 biology
Our data led us to propose the role of G-quadruplexes as non-B DNA recognition motifs of wild-type and mutant p53 protein for transcriptional regulation of p53 target genes....
Biochemistry and molecular biology
- 2018 •
- O
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