Menopause: clustering of metabolic syndrome components and population changes in insulin resistance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002458" target="_blank" >RIV/00023001:_____/11:00002458 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/11:43891858 RIV/00064190:_____/11:#0000156

Výsledek na webu

<a href="http://dx.doi.org/10.3109/13697131003692745" target="_blank" >http://dx.doi.org/10.3109/13697131003692745</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/13697131003692745" target="_blank" >10.3109/13697131003692745</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Menopause: clustering of metabolic syndrome components and population changes in insulin resistance

Popis výsledku v původním jazyce

Aim The incidence of the metabolic syndrome (MS) in women rises rapidly during the menopause, substantially increasing their cardiovascular risk and mortality. The aim of the study was to analyze menopausal changes in individual MS components and the parameter of insulin resistance (HOMA-IR). Methods A random population sample of 909 women aged 45--54 years, resident in Prague 4, was examined in an epidemiological study. After excluding women with gynecological hormone therapy or surgical therapy, the two groups of women were compared: women of reproductive age (REPRO, n == 245) vs. naturally postmenopausal women (POSTm, n == 149). Results The incidence of MS rose significantly in menopause (REPRO/POSTm 22.9 ?? 2.6%%/38.3 ?? 4.0%%; p < 0.001). However,a detailed analysis among the five components defining MS showed that increases were only seen in waist circumference ( p < 0.0001) and triglycerides ( p < 0.001). There was no increase in the other components or HOMA-IR. A detailed anal

Název v anglickém jazyce

Menopause: clustering of metabolic syndrome components and population changes in insulin resistance

Popis výsledku anglicky

Aim The incidence of the metabolic syndrome (MS) in women rises rapidly during the menopause, substantially increasing their cardiovascular risk and mortality. The aim of the study was to analyze menopausal changes in individual MS components and the parameter of insulin resistance (HOMA-IR). Methods A random population sample of 909 women aged 45--54 years, resident in Prague 4, was examined in an epidemiological study. After excluding women with gynecological hormone therapy or surgical therapy, the two groups of women were compared: women of reproductive age (REPRO, n == 245) vs. naturally postmenopausal women (POSTm, n == 149). Results The incidence of MS rose significantly in menopause (REPRO/POSTm 22.9 ?? 2.6%%/38.3 ?? 4.0%%; p < 0.001). However,a detailed analysis among the five components defining MS showed that increases were only seen in waist circumference ( p < 0.0001) and triglycerides ( p < 0.001). There was no increase in the other components or HOMA-IR. A detailed anal

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Climacteric

ISSN

1369-7137

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

83-91

Kód UT WoS článku

000287248000014

EID výsledku v databázi Scopus

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