Polymyositis: does it really exist as a distinct clinical subset?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023728%3A_____%2F21%3AN0000059" target="_blank" >RIV/00023728:_____/21:N0000059 - isvavai.cz</a>

Výsledek na webu

<a href="https://journals.lww.com/co-rheumatology/Abstract/2021/11000/Polymyositis__does_it_really_exist_as_a_distinct.12.aspx" target="_blank" >https://journals.lww.com/co-rheumatology/Abstract/2021/11000/Polymyositis__does_it_really_exist_as_a_distinct.12.aspx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/BOR.0000000000000837" target="_blank" >10.1097/BOR.0000000000000837</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Polymyositis: does it really exist as a distinct clinical subset?

Popis výsledku v původním jazyce

Purpose of review To summarize information on polymyositis; diagnosis, definitions, published data and opinions. Recent findings Polymyositis originally referred to inflammatory muscle diseases presenting with muscle weakness and inflammatory cell infiltrates on muscle tissue visible by microscopy. Over time and with improved technology to immunophenotype infiltrating inflammatory cells and characterize muscle fibres, the meaning of polymyositis changed and became more specific. There is ongoing controversy over the term polymyositis, with proponents for a strict definition based on histopathological and immunohistochemical features on muscle biopsies whereas others advocate for a broader clinical and histopathological phenotype. Over the past decades, the discovery of several myositis-specific autoantibodies together with distinct histopathological features have enabled the identification of new subsets previously labelled as polymyositis notably the antisynthetase syndrome and the immune-mediated necrotizing myopathies thus reducing the number of patients classified as polymyositis. There are still a small number of patients among the idiopathic inflammatory myopathies that can be classified as polymyositis as discussed in this review but the entity is now considered relatively rare.

Název v anglickém jazyce

Polymyositis: does it really exist as a distinct clinical subset?

Popis výsledku anglicky

Purpose of review To summarize information on polymyositis; diagnosis, definitions, published data and opinions. Recent findings Polymyositis originally referred to inflammatory muscle diseases presenting with muscle weakness and inflammatory cell infiltrates on muscle tissue visible by microscopy. Over time and with improved technology to immunophenotype infiltrating inflammatory cells and characterize muscle fibres, the meaning of polymyositis changed and became more specific. There is ongoing controversy over the term polymyositis, with proponents for a strict definition based on histopathological and immunohistochemical features on muscle biopsies whereas others advocate for a broader clinical and histopathological phenotype. Over the past decades, the discovery of several myositis-specific autoantibodies together with distinct histopathological features have enabled the identification of new subsets previously labelled as polymyositis notably the antisynthetase syndrome and the immune-mediated necrotizing myopathies thus reducing the number of patients classified as polymyositis. There are still a small number of patients among the idiopathic inflammatory myopathies that can be classified as polymyositis as discussed in this review but the entity is now considered relatively rare.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30226 - Rheumatology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Opinion Rheumatology

ISSN

1040-8711

e-ISSN

1531-6963

Svazek periodika

33

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

537-543

Kód UT WoS článku

000700561400012

EID výsledku v databázi Scopus

2-s2.0-85118096123