Nanoparticle-specific changes in Arabidopsis thaliana gene expression after exposure to ZnO, TiO2, and fullerene soot

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F12%3A00002262" target="_blank" >RIV/00027006:_____/12:00002262 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/12:00389142

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jhazmat.2012.08.059" target="_blank" >http://dx.doi.org/10.1016/j.jhazmat.2012.08.059</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jhazmat.2012.08.059" target="_blank" >10.1016/j.jhazmat.2012.08.059</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanoparticle-specific changes in Arabidopsis thaliana gene expression after exposure to ZnO, TiO2, and fullerene soot

Popis výsledku v původním jazyce

The effect of exposure to 100 mg/L zinc oxide (nZnO), fullerene soot (FS) or titanium dioxide (nTiO2)nanoparticles on gene expression in Arabidopsis thaliana roots was studied using microarrays. After 7 d,nZnO, FS, or nTiO2 exposure resulted in 660 up- and 826 down-regulated genes, 232 up- and 189 downregulated genes, and 80 up- and 74 down-regulated genes, respectively (expression difference > 2-fold; p[t test] < 0.05). The genes induced by nZnO and FS include mainly ontology groups annotated as stressresponsive, including both abiotic (oxidative, salt, water deprivation) and biotic (wounding and defense to pathogens) stimuli. The down-regulated genes upon nZnO exposure were involved in cell organization and biogenesis, including translation, nucleosome assembly and microtubule based process. FS largely repressed the transcription of genes involved in electron transport and energy pathways. Only mild changes in gene expression were observed upon nTiO2 exposure, which resulted in up-

Název v anglickém jazyce

Nanoparticle-specific changes in Arabidopsis thaliana gene expression after exposure to ZnO, TiO2, and fullerene soot

Popis výsledku anglicky

The effect of exposure to 100 mg/L zinc oxide (nZnO), fullerene soot (FS) or titanium dioxide (nTiO2)nanoparticles on gene expression in Arabidopsis thaliana roots was studied using microarrays. After 7 d,nZnO, FS, or nTiO2 exposure resulted in 660 up- and 826 down-regulated genes, 232 up- and 189 downregulated genes, and 80 up- and 74 down-regulated genes, respectively (expression difference > 2-fold; p[t test] < 0.05). The genes induced by nZnO and FS include mainly ontology groups annotated as stressresponsive, including both abiotic (oxidative, salt, water deprivation) and biotic (wounding and defense to pathogens) stimuli. The down-regulated genes upon nZnO exposure were involved in cell organization and biogenesis, including translation, nucleosome assembly and microtubule based process. FS largely repressed the transcription of genes involved in electron transport and energy pathways. Only mild changes in gene expression were observed upon nTiO2 exposure, which resulted in up-

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/LH11047" target="_blank" >LH11047: Rostliny a nanočástice - přátelé či nepřátele?</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Hazardous Materials

ISSN

0304-3894

e-ISSN

—

Svazek periodika

241

Číslo periodika v rámci svazku

November

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

55-62

Kód UT WoS článku

000313088300004

EID výsledku v databázi Scopus

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