The Transcriptomic Response of Arabidopsis thaliana to Zinc Oxide: A Comparison of the Impact of Nanoparticle, Bulk, and Ionic Zinc

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10315412" target="_blank" >RIV/00216208:11310/15:10315412 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389030:_____/15:00454866

Výsledek na webu

<a href="http://dx.doi.org/10.1021/acs.est.5b03330" target="_blank" >http://dx.doi.org/10.1021/acs.est.5b03330</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.est.5b03330" target="_blank" >10.1021/acs.est.5b03330</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Transcriptomic Response of Arabidopsis thaliana to Zinc Oxide: A Comparison of the Impact of Nanoparticle, Bulk, and Ionic Zinc

Popis výsledku v původním jazyce

The impact of nanosize was evaluated by comparing of the transcriptomic response of Arabidopsis thaliana roots to ZnO nanopartides (nZnO), bulk ZnO, and ionic Zn2+. Microarray analyses revealed 416 up- and 961 down-regulated transcripts (expression difference >2-fold, p [FDR] < 0.01) after a seven-day treatment with nZnO (average particle size 20 nm, concentration 4 mg L-1). Exposure to bulk ZnO resulted in 816 up- and 2179 down-regulated transcripts. The most dramatic changes (1711 transcripts up- and3242 down-regulated) were caused by the presence of ionic Zn2+ (applied as ZnSO4 center dot 7H(2)0 at a concentration of 14.14 mg L-1, corresponding to the amount of Zn contained in 4 mg L-1 ZnO). Genes involved in stress response (e.g., to salt, osmoticstress or water deprivation) were the most relatively abundant group of gene transcripts up-regulated by all three Zn treatments while genes involved in cell organization and biogenesis (e.g., tubulins, arabinogalactan proteins) and DNA

Název v anglickém jazyce

The Transcriptomic Response of Arabidopsis thaliana to Zinc Oxide: A Comparison of the Impact of Nanoparticle, Bulk, and Ionic Zinc

Popis výsledku anglicky

The impact of nanosize was evaluated by comparing of the transcriptomic response of Arabidopsis thaliana roots to ZnO nanopartides (nZnO), bulk ZnO, and ionic Zn2+. Microarray analyses revealed 416 up- and 961 down-regulated transcripts (expression difference >2-fold, p [FDR] < 0.01) after a seven-day treatment with nZnO (average particle size 20 nm, concentration 4 mg L-1). Exposure to bulk ZnO resulted in 816 up- and 2179 down-regulated transcripts. The most dramatic changes (1711 transcripts up- and3242 down-regulated) were caused by the presence of ionic Zn2+ (applied as ZnSO4 center dot 7H(2)0 at a concentration of 14.14 mg L-1, corresponding to the amount of Zn contained in 4 mg L-1 ZnO). Genes involved in stress response (e.g., to salt, osmoticstress or water deprivation) were the most relatively abundant group of gene transcripts up-regulated by all three Zn treatments while genes involved in cell organization and biogenesis (e.g., tubulins, arabinogalactan proteins) and DNA

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

—

Projekt

<a href="/cs/project/LD14125" target="_blank" >LD14125: Fytotoxicita nanovláken</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Environmental Science and Technology

ISSN

0013-936X

e-ISSN

—

Svazek periodika

49

Číslo periodika v rámci svazku

24

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

14537-14545

Kód UT WoS článku

000366872300076

EID výsledku v databázi Scopus

2-s2.0-84950108679