Vliv pektinu a amidovaného pektinu na homeostázi cholesterolu a metabolismus slepého střeva u potkanů krmených dietou s vysokým obsahem cholesterolu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F07%3A%230000472" target="_blank" >RIV/00027014:_____/07:#0000472 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/07:00089238 RIV/60461373:22330/07:00018355

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Effect of Pectin and Amidated Pectin on Cholesterol Homeostasis and Cecal Metabolism in Rats Fed a High-Cholesterol Diet

Popis výsledku v původním jazyce

The effect of pectin and its hydrophobic derivatives on homeostasis of cholesterol and cecal metabolism in rats was investigated. Rats were fed a diet with fat and cholesterol. Experimental rats were fed diet containing pectin or pectinamide. Pectinamideof 30% of amidation increased serum HDL cholesterol and pectinamide of 53% of amidation decreased total serum cholesterol. Amidated pectins decreased hepatic concentrations of cholesterol and fat. The highest cecal concentrations of short-chain fatty acids (SCFA) were in rats fed a pectin diet. In other groups, cecal SCFA was lower. Both pectinamides increased fecal cholesterol concentration. Hepatic tissue of control and pectin-fed rats was infiltrated with lipids. Thus, hydrophobic amidated pectins altered cholesterol homeostasis in rats and might be considered as effective hypocholesterolemic agents.

Název v anglickém jazyce

Effect of Pectin and Amidated Pectin on Cholesterol Homeostasis and Cecal Metabolism in Rats Fed a High-Cholesterol Diet

Popis výsledku anglicky

The effect of pectin and its hydrophobic derivatives on homeostasis of cholesterol and cecal metabolism in rats was investigated. Rats were fed a diet with fat and cholesterol. Experimental rats were fed diet containing pectin or pectinamide. Pectinamideof 30% of amidation increased serum HDL cholesterol and pectinamide of 53% of amidation decreased total serum cholesterol. Amidated pectins decreased hepatic concentrations of cholesterol and fat. The highest cecal concentrations of short-chain fatty acids (SCFA) were in rats fed a pectin diet. In other groups, cecal SCFA was lower. Both pectinamides increased fecal cholesterol concentration. Hepatic tissue of control and pectin-fed rats was infiltrated with lipids. Thus, hydrophobic amidated pectins altered cholesterol homeostasis in rats and might be considered as effective hypocholesterolemic agents.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GH - Výživa hospodářských zvířat

OECD FORD obor

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Projekt

<a href="/cs/project/GA525%2F03%2F0358" target="_blank" >GA525/03/0358: Příprava, popis struktury a biologické účinky derivátů pektinu</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Research

ISSN

0862-8408

e-ISSN

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Svazek periodika

56

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

10

Strana od-do

433-442

Kód UT WoS článku

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EID výsledku v databázi Scopus

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