Vývoj lymfatických orgánů u psa: hlavní populace a aktivita lymfocytů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F05%3A06000044" target="_blank" >RIV/00027162:_____/05:06000044 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lymphatic organ development in dogs: major lymphocyte subsets and activity

Popis výsledku v původním jazyce

In our study, we characterized lymphocyte subsets and activity in peripheral blood (PB), spleen, mesenteric and popliteal lymph nodes in pups from birth till the age of one month and compared the results with the group of three adult dogs. In neonatalpups, lower numbers of CD3+ T-cells were detected in both the spleen and PB than in lymph nodes. In contrast to the other compartments, CD21+ B-cells prevailed in the spleen. Low numbers of CD8+ lymphocytes were characteristic in all compartmentsimmediatelyafter birth. Postnatal development was characterized by an increasing frequency of CD8+ lymphocytes in all organs. Another feature of the early period of life was a relative decrease of B-cell, particularly in the PB and spleen. Stimulationindices uponmitogen-induced proliferation increased proportionally to the age. Based on our exper. data, we have concluded that pups are born with a relatively competent immune system the structure of which markedly develops during a few postnatal week

Název v anglickém jazyce

Lymphatic organ development in dogs: major lymphocyte subsets and activity

Popis výsledku anglicky

In our study, we characterized lymphocyte subsets and activity in peripheral blood (PB), spleen, mesenteric and popliteal lymph nodes in pups from birth till the age of one month and compared the results with the group of three adult dogs. In neonatalpups, lower numbers of CD3+ T-cells were detected in both the spleen and PB than in lymph nodes. In contrast to the other compartments, CD21+ B-cells prevailed in the spleen. Low numbers of CD8+ lymphocytes were characteristic in all compartmentsimmediatelyafter birth. Postnatal development was characterized by an increasing frequency of CD8+ lymphocytes in all organs. Another feature of the early period of life was a relative decrease of B-cell, particularly in the PB and spleen. Stimulationindices uponmitogen-induced proliferation increased proportionally to the age. Based on our exper. data, we have concluded that pups are born with a relatively competent immune system the structure of which markedly develops during a few postnatal week

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary Immunology and Immunopathology

ISSN

0165-2427

e-ISSN

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Svazek periodika

104

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

239-247

Kód UT WoS článku

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EID výsledku v databázi Scopus

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