Posouzení rizik možné mykobakteriální infekce (humánní tuberkulóza a aviární mykobakterióza) během anatomické pitvy lidského těla

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F06%3A%230000121" target="_blank" >RIV/00027162:_____/06:#0000121 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/06:10223790

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Risk assessment of mycobacterial infections (human tuberculosis and avian mycobacteriosis) during anatomical dissection of cadavers

Popis výsledku v původním jazyce

The aim was to study the presence of mycobacteria in tissue samples from 4 cadavers fixed with formalin and tissue samples from a recently deceased unpreserved individual who had a history of TBC. The samples were taken from 4 embalmed cadavers and 1 cadaver unpreserved undergoing a post mortem. All were examined for the presence of TB legions and the specific presence of MTC and MAC members by microscopy, culture, PCR analysis of 4 genomic elements (IS6110,mtp40,IS901,IS1245). Microscopy and culture examination for the presence of mycobacteria was negative in 22 tissue samples from the 4 embalmed cadavers. PCR of IS6110 and mtp40 was positive in tissue samples of TB lesions from the lungs of 2 embalmed cadavers and from intact kidney of 1 of these cadavers. Microscopy and culture examination of liver and spleen from the unpreserved cadaver were positive for mycobacteria. IS901 and IS1245 PCR, specific for M.a.avium, were positive in both tissue samples with and without TB lesions.

Název v anglickém jazyce

Risk assessment of mycobacterial infections (human tuberculosis and avian mycobacteriosis) during anatomical dissection of cadavers

Popis výsledku anglicky

The aim was to study the presence of mycobacteria in tissue samples from 4 cadavers fixed with formalin and tissue samples from a recently deceased unpreserved individual who had a history of TBC. The samples were taken from 4 embalmed cadavers and 1 cadaver unpreserved undergoing a post mortem. All were examined for the presence of TB legions and the specific presence of MTC and MAC members by microscopy, culture, PCR analysis of 4 genomic elements (IS6110,mtp40,IS901,IS1245). Microscopy and culture examination for the presence of mycobacteria was negative in 22 tissue samples from the 4 embalmed cadavers. PCR of IS6110 and mtp40 was positive in tissue samples of TB lesions from the lungs of 2 embalmed cadavers and from intact kidney of 1 of these cadavers. Microscopy and culture examination of liver and spleen from the unpreserved cadaver were positive for mycobacteria. IS901 and IS1245 PCR, specific for M.a.avium, were positive in both tissue samples with and without TB lesions.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/1B53009" target="_blank" >1B53009: Aviární tuberkulóza a mykobakteriózy: rozvoj metod pro jejich prevenci a tlumení studiem zdrojů infekce a patogeneze</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

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Svazek periodika

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Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

5

Kód UT WoS článku

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EID výsledku v databázi Scopus

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