Funkční vývoj imunitního systému u králíků

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F07%3A%230000215" target="_blank" >RIV/00027162:_____/07:#0000215 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Functional development of immune response in rabbits

Popis výsledku v původním jazyce

The aim of study was to extend knowledge concerning development of the immune system in rabbits from two aspects. Firstly, capability of lymphocytes from blood, spleen, and lymph nodes to respond to Concanavalin A stimulation was investigated. Secondly,changes in the ability to produce antibodies against tetanus toxoid by rabbits during maturation were studied. Proliferation of lymphocytes was reduced in mesenteric lymph nodes in newborns, in blood up to the age of 2 weeks, and in popliteal lymph nodesup to the age of 4 weeks when compared to adults. High spontaneous lymphocyte proliferation that lasted up to the age of 2 weeks was recorded in spleen. The study of antibody response showed that even one-day-old rabbits were able to form specific antibodies of isotype IgM and IgG. Nevertheless, lower formation of both isotypes was noted in one-day and 2-week-old rabbits, and commencement of IgG isotype formation was delayed in one day, 2-week, and 4-week-old rabbits when compared to ad

Název v anglickém jazyce

Functional development of immune response in rabbits

Popis výsledku anglicky

The aim of study was to extend knowledge concerning development of the immune system in rabbits from two aspects. Firstly, capability of lymphocytes from blood, spleen, and lymph nodes to respond to Concanavalin A stimulation was investigated. Secondly,changes in the ability to produce antibodies against tetanus toxoid by rabbits during maturation were studied. Proliferation of lymphocytes was reduced in mesenteric lymph nodes in newborns, in blood up to the age of 2 weeks, and in popliteal lymph nodesup to the age of 4 weeks when compared to adults. High spontaneous lymphocyte proliferation that lasted up to the age of 2 weeks was recorded in spleen. The study of antibody response showed that even one-day-old rabbits were able to form specific antibodies of isotype IgM and IgG. Nevertheless, lower formation of both isotypes was noted in one-day and 2-week-old rabbits, and commencement of IgG isotype formation was delayed in one day, 2-week, and 4-week-old rabbits when compared to ad

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary Immunology and Immunopathology

ISSN

0165-2427

e-ISSN

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Svazek periodika

118

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

221-228

Kód UT WoS článku

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EID výsledku v databázi Scopus

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