Characterisation of Enterococcus faecium CCDM 922 in respect of its technological and probiotic properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F16%3AN0000011" target="_blank" >RIV/00027162:_____/16:N0000011 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.ijcmas.com/5-5-2016/Ivana%20Hyrslova,%20et%20al.pdf" target="_blank" >http://www.ijcmas.com/5-5-2016/Ivana%20Hyrslova,%20et%20al.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.20546/ijcmas.2016.505.049" target="_blank" >10.20546/ijcmas.2016.505.049</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Characterisation of Enterococcus faecium CCDM 922 in respect of its technological and probiotic properties

Popis výsledku v původním jazyce

The aim of this study was to characterize the adherence, immunomodulatory and other health properties and safety of Enterococcus faecium CCDM 922 from the Culture Collection of Dairy Microorganisms Laktoflora®. E. faecium CCDM 922 is susceptible to therapeutically important antibiotics and exhibits good adherence to Caco-2 cells (52.33 ± 10.11 %). Two different concentrations of E. faecium CCDM 922 were used for three and five-day stimulation of human mononuclear cells obtained from peripheral blood. Levels of IFN-γ, IL-6, IL-10, IL-17 and IL-1α were dependent on the density of E. faecium CCDM 922 used for stimulation and on time of stimulation. The cholesterol-lowering effect of E. faecium CCDM 922 was tested in Prague hereditary hypercholesterolemic rats. E. faecium CCDM 922 treatment of male rats reduced LDL- and VLDL-cholesterol levels significantly (P < 0.05). Present results indicated promising probiotic and technological potential for application of E. faecium CCDM 922 in functional foods or dairy products.

Název v anglickém jazyce

Characterisation of Enterococcus faecium CCDM 922 in respect of its technological and probiotic properties

Popis výsledku anglicky

The aim of this study was to characterize the adherence, immunomodulatory and other health properties and safety of Enterococcus faecium CCDM 922 from the Culture Collection of Dairy Microorganisms Laktoflora®. E. faecium CCDM 922 is susceptible to therapeutically important antibiotics and exhibits good adherence to Caco-2 cells (52.33 ± 10.11 %). Two different concentrations of E. faecium CCDM 922 were used for three and five-day stimulation of human mononuclear cells obtained from peripheral blood. Levels of IFN-γ, IL-6, IL-10, IL-17 and IL-1α were dependent on the density of E. faecium CCDM 922 used for stimulation and on time of stimulation. The cholesterol-lowering effect of E. faecium CCDM 922 was tested in Prague hereditary hypercholesterolemic rats. E. faecium CCDM 922 treatment of male rats reduced LDL- and VLDL-cholesterol levels significantly (P < 0.05). Present results indicated promising probiotic and technological potential for application of E. faecium CCDM 922 in functional foods or dairy products.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Current Microbiology and Applied Sciences

ISSN

2319-7692

e-ISSN

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Svazek periodika

5

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

IN - Indická republika

Počet stran výsledku

9

Strana od-do

474-482

Kód UT WoS článku

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EID výsledku v databázi Scopus

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