Low Initial Adherence with Flash Glucose Monitoring is Not a Predictor of Long-Term Glycemic Outcomes: Longitudinal Analysis of the Association Between Experience, Adherence, and Glucose Control for FreeStyle Libre Users

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F23%3A10465923" target="_blank" >RIV/00064165:_____/23:10465923 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/23:10465923

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=.1frjcqNz1" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=.1frjcqNz1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s13300-023-01422-4" target="_blank" >10.1007/s13300-023-01422-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Low Initial Adherence with Flash Glucose Monitoring is Not a Predictor of Long-Term Glycemic Outcomes: Longitudinal Analysis of the Association Between Experience, Adherence, and Glucose Control for FreeStyle Libre Users

Popis výsledku v původním jazyce

Introduction: Frequent scanning of FreeStyle Libre (FSL) flash glucose monitoring sensors is known to be important whilst wearing an active sensor, but adherence to sensor reapplication is also critical to effective glucose monitoring. We report novel measures of adherence for users of the FSL system and their association with improvements in metrics of glucose control. Methods: Anonymous data were extracted for 1600 FSL users in the Czech Republic with &gt;= 36 completed sensors from October 22, 2018 to December 31, 2021. &quot;Experience&quot; was defined by the number of sensors used (1-36 sensors). &quot;Adherence&quot; was defined by time between the end of one sensor and the start of the next (gap time). User adherence was analyzed for four experience levels after initiating FLASH; Start (sensors 1-3); Early (sensors 4-6); Middle (sensors 19-21); End (sensors 34-36). Users were split into two adherence levels based on mean gap time during Start period, &quot;low&quot; (&gt; 24 h, n = 723) and &quot;high&quot; (&lt;= 8 h, n = 877). Results: Low-adherence users reduced their sensor gap times significantly: 38.5% applied a new sensor within 24 h during sensors 4-6, rising to 65.0% by sensors 34-36 (p &lt; 0.001). Improved adherence was associated with increased %TIR (time in range; mean + 2.4%; p &lt; 0.001), reduced %TAR (time above range; mean - 3.1%; p &lt; 0.001), and reduced glucose coefficient of variation (CV; mean - 1.7%; p &lt; 0.001). Conclusions: With experience, FSL users became more adherent in sensor reapplication, with associated increases in %TIR, and reductions in %TAR and glucose variability.

Název v anglickém jazyce

Low Initial Adherence with Flash Glucose Monitoring is Not a Predictor of Long-Term Glycemic Outcomes: Longitudinal Analysis of the Association Between Experience, Adherence, and Glucose Control for FreeStyle Libre Users

Popis výsledku anglicky

Introduction: Frequent scanning of FreeStyle Libre (FSL) flash glucose monitoring sensors is known to be important whilst wearing an active sensor, but adherence to sensor reapplication is also critical to effective glucose monitoring. We report novel measures of adherence for users of the FSL system and their association with improvements in metrics of glucose control. Methods: Anonymous data were extracted for 1600 FSL users in the Czech Republic with &gt;= 36 completed sensors from October 22, 2018 to December 31, 2021. &quot;Experience&quot; was defined by the number of sensors used (1-36 sensors). &quot;Adherence&quot; was defined by time between the end of one sensor and the start of the next (gap time). User adherence was analyzed for four experience levels after initiating FLASH; Start (sensors 1-3); Early (sensors 4-6); Middle (sensors 19-21); End (sensors 34-36). Users were split into two adherence levels based on mean gap time during Start period, &quot;low&quot; (&gt; 24 h, n = 723) and &quot;high&quot; (&lt;= 8 h, n = 877). Results: Low-adherence users reduced their sensor gap times significantly: 38.5% applied a new sensor within 24 h during sensors 4-6, rising to 65.0% by sensors 34-36 (p &lt; 0.001). Improved adherence was associated with increased %TIR (time in range; mean + 2.4%; p &lt; 0.001), reduced %TAR (time above range; mean - 3.1%; p &lt; 0.001), and reduced glucose coefficient of variation (CV; mean - 1.7%; p &lt; 0.001). Conclusions: With experience, FSL users became more adherent in sensor reapplication, with associated increases in %TIR, and reductions in %TAR and glucose variability.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Diabetes Therapy

ISSN

1869-6953

e-ISSN

1869-6961

Svazek periodika

14

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

1231-1240

Kód UT WoS článku

000991626100001

EID výsledku v databázi Scopus

2-s2.0-85160248853