High-flow nasal cannula for stabilisation of very premature infants: A prospective observational study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F25%3A10489053" target="_blank" >RIV/00064165:_____/25:10489053 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/68407700:21460/25:00378198 RIV/00216208:11110/25:10489053
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=B92_JP~rga" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=B92_JP~rga</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/apa.17519" target="_blank" >10.1111/apa.17519</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
High-flow nasal cannula for stabilisation of very premature infants: A prospective observational study
Popis výsledku v původním jazyce
Aim: To assess the feasibility, safety and efficacy of using a high-flow nasal cannula (HFNC) for stabilising very preterm infants after birth. Methods: A prospective observational study included preterm infants born at 28 + 0 to 31 + 6 weeks' gestation between February 2021 and December 2022 at the General University Hospital in Prague. Following delayed cord clamping, HFNC was administered at a flow rate of 8 L/min through the infants' nostrils. Criteria for switching to continuous positive airway pressure (CPAP) or positive pressure ventilation (PPV) included persistent bradycardia in the first few minutes or low saturation of oxygen (SpO(2)) after 5 min, respectively. Results: Of the 65 infants enrolled in the study, 56 (86%) were successfully stabilised exclusively using HFNC while 7 (11%) required PPV. Additionally, 52 (80%) infants achieved SpO(2) > 80% at 5 min, and 54 (83%) infants were successfully treated with HFNC within the first 3 h of life. Conclusion: The primary use of HFNC seems to be an appropriate alternative to CPAP for the stabilisation of very premature infants after birth and subsequent transfer to the NICU. A randomised trial comparing HFNC and CPAP in the delivery room will enable to answer the questions raised in this study.
Název v anglickém jazyce
High-flow nasal cannula for stabilisation of very premature infants: A prospective observational study
Popis výsledku anglicky
Aim: To assess the feasibility, safety and efficacy of using a high-flow nasal cannula (HFNC) for stabilising very preterm infants after birth. Methods: A prospective observational study included preterm infants born at 28 + 0 to 31 + 6 weeks' gestation between February 2021 and December 2022 at the General University Hospital in Prague. Following delayed cord clamping, HFNC was administered at a flow rate of 8 L/min through the infants' nostrils. Criteria for switching to continuous positive airway pressure (CPAP) or positive pressure ventilation (PPV) included persistent bradycardia in the first few minutes or low saturation of oxygen (SpO(2)) after 5 min, respectively. Results: Of the 65 infants enrolled in the study, 56 (86%) were successfully stabilised exclusively using HFNC while 7 (11%) required PPV. Additionally, 52 (80%) infants achieved SpO(2) > 80% at 5 min, and 54 (83%) infants were successfully treated with HFNC within the first 3 h of life. Conclusion: The primary use of HFNC seems to be an appropriate alternative to CPAP for the stabilisation of very premature infants after birth and subsequent transfer to the NICU. A randomised trial comparing HFNC and CPAP in the delivery room will enable to answer the questions raised in this study.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30200 - Clinical medicine
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2025
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Acta Paediatrica
ISSN
0803-5253
e-ISSN
1651-2227
Svazek periodika
114
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
986-991
Kód UT WoS článku
001363128400001
EID výsledku v databázi Scopus
2-s2.0-85210099538